Last updated on 5 December 2013 
Cleveland Meat Company prosecution
The FSA has welcomed the successful prosecution of the Cleveland Meat 
Company Ltd for breaches of food safety regulations. The company has been 
ordered to pay more than £27,000 in fines and prosecution costs after being 
found guilty on 12 charges. It entered a guilty plea on a 13th charge during the 
course of the hearing.
The FSA brought the prosecution against the Cleveland Meat Company after 
FSA staff identified breaches of the regulations, which are in place to prevent 
potential consumer exposure to BSE. These breaches included the failure to 
remove specified risk material (SRM) from a sheep carcass. SRM are the parts of 
the animal most likely to carry infectivity.
Andrew Rhodes, Chief Operating Officer of the FSA, said: 'We are pleased 
with the successful conclusion of this prosecution. These regulations are in 
place to keep the public safe and the FSA’s job is to ensure they are enforced 
properly across the country. Where companies are not meeting their 
responsibilities we will take action.' 
THAT AIN’T BAD, only $27,000 fine for exposing the consumers to a disease 
that is 100% fatal, once clinical, and really, no way to trace the potential 
iatrogenic TSE there from to humans. all iatrogenic CJD is, is sporadic CJD, 
until the iatrogenic event that took place is identified, confirmed, and then 
put in the academic domain, and that rarely ever happens $$$...TSS
why do we not want to do TSE transmission studies on chimpanzees $ 
*** 5. A positive result from a chimpanzee challenged severly would likely 
create alarm in some circles even if the result could not be interpreted for 
man. I have a view that all these agents could be transmitted provided a large 
enough dose by appropriate routes was given and the animals kept long enough. 
Until the mechanisms of the species barrier are more clearly understood it might 
be best to retain that hypothesis. 
snip... 
R. BRADLEY 
1: J Infect Dis 1980 Aug;142(2):205-8 
Oral transmission of kuru, Creutzfeldt-Jakob disease, and scrapie to 
nonhuman primates. 
Gibbs CJ Jr, Amyx HL, Bacote A, Masters CL, Gajdusek DC. 
Kuru and Creutzfeldt-Jakob disease of humans and scrapie disease of sheep 
and goats were transmitted to squirrel monkeys (Saimiri sciureus) that were 
exposed to the infectious agents only by their nonforced consumption of known 
infectious tissues. The asymptomatic incubation period in the one monkey exposed 
to the virus of kuru was 36 months; that in the two monkeys exposed to the virus 
of Creutzfeldt-Jakob disease was 23 and 27 months, respectively; and that in the 
two monkeys exposed to the virus of scrapie was 25 and 32 months, respectively. 
Careful physical examination of the buccal cavities of all of the monkeys failed 
to reveal signs or oral lesions. One additional monkey similarly exposed to kuru 
has remained asymptomatic during the 39 months that it has been under 
observation. 
snip... 
*** The successful transmission of kuru, Creutzfeldt-Jakob disease, and 
scrapie by natural feeding to squirrel monkeys that we have reported provides 
further grounds for concern that scrapie-infected meat may occasionally give 
rise in humans to Creutzfeldt-Jakob disease. 
PMID: 6997404 
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=6997404&dopt=Abstract 
Recently the question has again been brought up as to whether scrapie is 
transmissible to man. This has followed reports that the disease has been 
transmitted to primates. One particularly lurid speculation (Gajdusek 1977) 
conjectures that the agents of scrapie, kuru, Creutzfeldt-Jakob disease and 
transmissible encephalopathy of mink are varieties of a single "virus". The U.S. 
Department of Agriculture concluded that it could "no longer justify or permit 
scrapie-blood line and scrapie-exposed sheep and goats to be processed for human 
or animal food at slaughter or rendering plants" (ARC 84/77)" The problem is 
emphasised by the finding that some strains of scrapie produce lesions identical 
to the once which characterise the human dementias" 
Whether true or not. the hypothesis that these agents might be 
transmissible to man raises two considerations. First, the safety of laboratory 
personnel requires prompt attention. Second, action such as the "scorched meat" 
policy of USDA makes the solution of the acrapie problem urgent if the sheep 
industry is not to suffer grievously. 
snip... 
76/10.12/4.6 
Nature. 1972 Mar 10;236(5341):73-4. 
Transmission of scrapie to the cynomolgus monkey (Macaca fascicularis). 
Gibbs CJ Jr, Gajdusek DC. 
Nature 236, 73 - 74 (10 March 1972); doi:10.1038/236073a0 
Transmission of Scrapie to the Cynomolgus Monkey (Macaca fascicularis) 
C. J. GIBBS jun. & D. C. GAJDUSEK 
National Institute of Neurological Diseases and Stroke, National Institutes 
of Health, Bethesda, Maryland 
SCRAPIE has been transmitted to the cynomolgus, or crab-eating, monkey 
(Macaca fascicularis) with an incubation period of more than 5 yr from the time 
of intracerebral inoculation of scrapie-infected mouse brain. The animal 
developed a chronic central nervous system degeneration, with ataxia, tremor and 
myoclonus with associated severe scrapie-like pathology of intensive astroglial 
hypertrophy and proliferation, neuronal vacuolation and status spongiosus of 
grey matter. The strain of scrapie virus used was the eighth passage in Swiss 
mice (NIH) of a Compton strain of scrapie obtained as ninth intracerebral 
passage of the agent in goat brain, from Dr R. L. Chandler (ARC, Compton, 
Berkshire). 
Wednesday, February 16, 2011 
IN CONFIDENCE 
SCRAPIE TRANSMISSION TO CHIMPANZEES 
IN CONFIDENCE 
Monday, December 02, 2013 
A parliamentary inquiry has been launched today into the safety of blood, 
tissue and organ screening following fears that vCJD – the human form of ‘mad 
cow’ disease – may be being spread by medical procedures 
Tuesday, November 5, 2013 
Food Standards Agency FSA 13/11/05 Open Board – 05 November 2013 BSE 
Thursday, June 6, 2013 
FSA MORE BSE MAD COW CONTROL BREACHES JUNE 2013 
Friday, October 25, 2013 
UK FSA TSE BSE Board meeting agenda: 5 November 2013 
Wednesday, March 27, 2013 
U-turn considered on European PAP animal feed ban 27 Mar 2013 News 
Tuesday, March 5, 2013 
FSA notified of BSE control breaches again and again 5 March 2013 
Thursday, January 17, 2013 
FSA notified of two breaches of BSE testing regulations 14 January 2013 
Food Standards Agency FSA 13/01/01 Open Board – 22 January 2013 
PROPOSED DECISION TO STOP BSE TESTING OF HEALTHY CATTLE SLAUGHTERED FOR 
HUMAN CONSUMPTION (FSA 12/12/04) 
snip... 
12. The Deputy Chair declared an interest as an owner of a small farm, but 
had no livestock. The Chair agreed that this would not improperly influence the 
Deputy Chair’s contributions to the discussion.
13. The Chair welcomed Alison Gleadle, FSA Director of Food Safety, David 
Carruthers, FSA Head of Meat Hygiene and TSE Policy Branch and Alick Simmons, 
Deputy Chief Veterinary Officer, Defra to the meeting. Alison Gleadle explained 
that the critical controls to protect human health and prevent a recurrence of 
BSE were those associated with the removal of Specified Risk Material (SRM) from 
carcases and the control of feed stuffs. The current proposal to stop BSE 
testing healthy slaughter cattle was based on European Food Safety Authority 
(EFSA) advice and relates to surveillance rather than consumer protection. This 
advice was consistent with previous advice from the Spongiform Encephalopathy 
Advisory Committee (SEAC) that any change in BSE incidence is most likely to be 
detected in at risk cattle. The letter from the Chief Medical Officer also 
agreed with this assessment. No change was proposed to the SRM or feed ban 
controls. Alison Gleadle assured the Board that if there were any unexpected 
changes in BSE levels or deterioration in the epidemiological situation, the 
Board would be informed.
14. Alick Simmons said Defra, as the Department responsible for overseeing 
the surveillance system, was committed to managing the risk to public health on 
a proportionate basis.
15. A Board member agreed the science supported the recommendation in the 
paper but wanted assurance that sufficient testing would remain in place to spot 
any re-emergence of BSE and wanted to know if it would take longer to detect an 
increase. Alick Simmons said this would not be the beginning of the end of 
monitoring. Internationally the UK has controlled risk status. It would take 11 
years after the birth of the last BSE case before the UK achieved negligible 
risk status and could 
Food Standards Agency FSA 13/01/01 Open Board – 22 January 2013 4 
reduce the controls. The current sensitive controls made predictions of 
re-emergence easier and would remain in place. There could be a change in the 
speed with which a re-emergence of the disease could be detected but as long as 
the SRM and feed controls remained in place the effects of any delay would be 
significantly mitigated.
16. The Chair of the Scottish Food Advisory Committee (SFAC) said the 
Committee agreed with the recommendation but it was crucial that the two 
controls (feed ban and SRM) remained in place. He asked if the FSA would have to 
wait 17 years to detect a re-emergence or if the continued testing of at-risk 
cattle would detect it before then. Alick Simmons said he would expect to see 
any re-emergence in at-risk cattle. The results of the monitoring undertaken by 
Defra were published. AHVLA run a model every year on the data so any change in 
the level of BSE detected would come to the FSA’s attention as soon as that data 
was reported.
17. The Chair of the Welsh Food Advisory Committee (WFAC) said the 
Committee supported moving to the modified regime but it was a pre-requisite 
that the controls (feed ban and SRM) remained in place and regular reports on 
the effectiveness of the monitoring system were provided. These reports would be 
expected to include information on the feed ban although the enforcement of it 
is not part of the FSA’s remit.
18. On behalf of the Chair of the Northern Ireland Food Advisory Committee 
(NIFAC), the Chair said NIFAC also sought reassurance on the integrity of the 
surveillance of fallen and at-risk cattle.
19. The Deputy Chair said that while the FSA would be involved in any 
changes to the TSE Road map, it would not be involved in any changes to animal 
health surveillance and stressed that communication between Defra and the FSA on 
this latter point would be crucial. The Chief Executive drew the Board’s 
attention to the letter from Peter Unwin, Director General of Policy Delivery at 
Defra, which states that the FSA’s advice will be sought on the food safety 
implications of any proposals to change the BSE testing requirements.
20. The Deputy Chair said Bulgaria and Romania were high risk countries and 
asked if traceability systems existed to cope with a two tier system. Alick 
Simmons said that Romania and Bulgaria were not necessarily higher risk but as 
their controls had been in place for a shorter period, they could not yet move 
to a lower level of surveillance. He said there were statutory requirements on 
surveillance of foreign stock, on diseases other than BSE and additional tests 
for new and emerging diseases. Defra expected to start a consultation on 13 
December 2012 to reconfigure the surveillance system for new and emerging 
diseases in England and Wales. Alick Simmons invited Board members to attend the 
AHVLA meetings as part of their consultation on changes to wider surveillance 
systems for new and emerging diseases. 
Action: Deputy Chief Veterinary Officer Food Standards Agency FSA 13/01/01 
Open Board – 22 January 2013 
5 21. A Board member suggested adding the following wording to the FSA 
advice to Ministers: “while continuing to test all “risk cattle” aged over 48 
months and subject to maintaining the ban on feeding animal protein to farmed 
animals and the removal of specified risk material (SRM).”
22. The Chair said the risk to consumers of stopping BSE testing of all 
healthy cattle aged over 72 months was negligible and the food supply chain 
would continue to be protected with the ban on animal protein in animal feed and 
the removal of specified risk material (SRM). With no case of BSE in healthy 
snip... 
11Dec12/O/22 
Director of Food Safety
The Board should review a report on the results of the BSE monitoring 
system and the effectiveness of enforcement of the feed and SRM controls six 
months after current levels of BSE testing are reduced; a second report after 
another six months; and then a report annually.
Nov 2013
This has been noted and placed on the future agenda plan. 
Citizens Forums are the main mechanism for direct engagement with consumers 
across the UK. Forums can either be a longer deliberative process where more 
information is required and consumers need time to think more widely about the 
issues. For other policy issues a shorter one-session discussion is used e.g. 
changes to BSE testing.
Locations are chosen to ensure ethnic diversity and consumers with 
non-English cultures are included. This involves selecting locations with rich 
ethnic diversity e.g. Birmingham, Bradford, Leicester and London. On some policy 
issues the closeness to agriculture or farming has made a difference to how 
consumers view particular challenges. Recent examples of this include Processed 
Animal Protein (PAP), EU Proposals on BSE Regulation and Consumer Attitudes to 
Raw Drinking Milk. Therefore ensuring consumers from areas that are more rurally 
located and not just cities or large towns has ensured the engagement does not 
become one dimensional. 
breaches (UK)
In the period 1 April 2012 to 30 September 2012, 1,277,136 bovines were 
slaughtered for human consumption, with 5 breaches of BSE controls reported in 
the period. During Quarter 2 (July – September 2012) there were 4 breaches and 
643,732 bovines were slaughtered for human consumption. None of these breaches 
were for bovines included in FSA checks. All specified risk material would have 
been removed from the animals at the time of processing (specified risk material 
is the parts of an animal likely to contain any infectivity in the unlikely 
event that the animal should have BSE). 
> This has been noted and placed on the future agenda plan. 
? 
 TSS 
TO STOP TESTING HEALTHY CATTLE FOR BSE TSE PRION DISEASE, all strains, it 
just seems so counter productive to me, and further risk spreading the BSE TSE 
prion agent even further, thus risking more humans...tss 
“This research raises the possibility, which has been mentioned before, 
that apparently healthy cattle could harbour, but never show signs of, BSE.” 
SUB CLINICAL PRION INFECTION
MRC-43-00 Issued: Monday, 28 August 2000
NEW EVIDENCE OF SUB-CLINICAL PRION INFECTION: IMPORTANT RESEARCH FINDINGS 
RELEVANT TO CJD AND BSE
A team of researchers led by Professor John Collinge at the Medical 
Research Council Prion Unit1 report today in the Proceedings of the National 
Academy of Sciences, on new evidence for the existence of a ?sub-clinical? form 
of BSE in mice which was unknown until now. 
"This is a timely and unexpected result, increasing what we know about 
prion disease. These new findings have important implications for those 
researching prion disease, those responsible for preventing infected material 
getting into the food chain and for those considering how best to safeguard 
health and reduce the risk that theoretically, prion disease could be contracted 
through medical and surgical procedures." 
ISSUED FRIDAY 25 AUGUST UNDER EMBARGO. PLEASE NOTE THAT THE EMBARGO IS SET 
BY THE JOURNAL 
see full text ; 
Neurobiology of Disease
Subclinical Bovine Spongiform Encephalopathy Infection in Transgenic Mice 
Expressing Porcine Prion Protein 
Friday, December 21, 2012 
Four BSE cases with an L-BSE molecular profile in cattle from Great Britain 
Veterinary Record doi:10.1136/vr.101158 Paper 
Monday, October 14, 2013 
Researchers estimate one in 2,000 people in the UK carry variant CJD 
proteins 
Tuesday, October 29, 2013 
VARIANT CJD PRESENTS DIFFERENTLY IN OLDER PATIENTS 
Wednesday, October 09, 2013 
*** WHY THE UKBSEnvCJD ONLY THEORY IS SO POPULAR IN IT'S FALLACY, 
£41,078,281 in compensation REVISED 
Thursday, October 10, 2013 
CJD REPORT 1994 increased risk for consumption of veal and venison and lamb 
Friday, August 16, 2013 
*** Creutzfeldt-Jakob disease (CJD) biannual update August 2013 U.K. and 
Contaminated blood products induce a highly atypical prion disease devoid of 
PrPres in primates 
WHAT about the sporadic CJD TSE proteins ? 
WE now know that some cases of sporadic CJD are linked to atypical BSE and 
atypical Scrapie, so why are not MORE concerned about the sporadic CJD, and all 
it’s sub-types $$$ 
Creutzfeldt-Jakob Disease CJD cases rising North America updated report 
August 2013 
*** Creutzfeldt-Jakob Disease CJD cases rising North America with Canada 
seeing an extreme increase of 48% between 2008 and 2010 *** 
Sunday, October 13, 2013 
CJD TSE Prion Disease Cases in Texas by Year, 2003-2012 
Monday, September 02, 2013
Lessons from the response to the threat of transfusion-transmitted vCJD in 
Ireland 
Saturday, November 2, 2013 
Recommendation of the Swiss Expert Committee for Biosafety on the 
classification of activities using prion genes and prion protein January 2013 
Wednesday, December 4, 2013 
Bovine Spongiform Encephalopathy; Importation of Bovines and Bovine 
Products; Final Rule Federal Register / Vol. 78 , No. 233 / Wednesday, December 
4, 2013 
TO ALL IMPORTING COUNTRIES THAT IMPORTS FROM THE USA, BE WARNED, NEW MAD 
COW BSE REGULATIONS USDA, AND OIE, not worth the paper the regulations were 
wrote on, kind of like the mad cow feed ban of August 1997, nothing but ink on 
paper $$$
full text ;
Thursday, December 05, 2013 
National Scrapie Eradication Program October 2013 Monthly Report Fiscal 
Year 2014 TSE PRION REPORT 
TSS
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