atypical BSE Mad cow disease found in Switzerland March 12, 2012

Monday, 12 March, 2012, 13:52

Mad cow strain found in Switzerland

The Federal Veterinary Office has confirmed one case of mad cow disease in the canton of Bern. The cow was slaughtered last month. The case was discovered as part of a monitoring programme implemented by Swiss authorities. According to vets the cow was not infected with a classical case of BSE, but rather an atypical strain. They say that means the disease was not triggered by a certain animal feed outlawed in 2005. The cow was imported to Switzerland in 2006. Until this case, no cows with BSE have been found in Switzerland since 2007. The Federal Veterinary Office confirms it may have found another one of these atypical cases but stresses this strain of disease is rare. BSE was first diagnosed in 1990, and since then 467 cows were diagnosed with it in Switzerland. No cases of the human strain have ever been detected here.

http://worldradio.ch/wrs/news/wrsnews/mad-cow-disease-strain-in-switzerland.shtml?29563





on the official government site for BSE, it’s not in English. ...TSS



BSE-Fall bei einer importierten Kuh

Bern, 12.03.2012 - Im Rahmen des offiziellen Überwachungsprogrammes wurde bei einer Kuh eines Betriebes im Kanton Bern BSE festgestellt. Analysen zeigen jedoch, dass es sich nicht um einen Fall von klassischer BSE handelt, sondern um eine sogenannte atypische BSE. Das Tier stammte aus Deutschland und wurde 2006 in die Schweiz importiert.

Der aktuelle Fall ändert nichts an der guten Lage bezüglich BSE in der Schweiz. Bis 2006 hatten sich die Fälle stark vermindert, zwischen 2007 und 2011 wurden überhaupt keine Fälle mehr diagnostiziert. Aber die letzten Fälle erinnern daran, dass wir trotz dieser vorteilhaften Situation doch vereinzelt mit Fällen von BSE rechnen müssen.

Die Diagnostik des Referenzlabors zeigt, dass es sich nicht um einen typischen Fall von BSE, sondern um einen sogenannt atypischen BSE-Fall handelt. Seit einigen Jahren werden in verschiedenen europäischen Ländern vereinzelt solche atypische Fälle von BSE festgestellt. Die Wissenschaftler glauben, dass diese Form der BSE möglicherweise eine sporadisch auftauchende Krankheit ist, die nicht auf infektiöses Material im Futter zurückzuführen ist. Im Gegensatz dazu werden die typischen BSE-Fälle durch infektiöses Material im Futter der Tiere verursacht.

Beim verseuchten Tier handelt es sich um eine bald 7-jährige Kuh welche im April 2005 in Deutschland geboren und im November 2006 in die Schweiz importiert wurde. Die Kuh musste wegen Festliegens nach der Geburt geschlachtet werden und wurde deshalb routinemässig labordiagnostisch untersucht. Dabei wurde BSE diagnostiziert. Seit dem ersten Schweizer Fall im Jahre 1990 wurden in der Schweiz insgesamt 467 BSE-Fälle gemeldet. Mit Ausnahme eines Falles in 2011 waren alle betroffenen Rinder vor dem totalen Tiermehlverfütterungsverbot vom Januar 2001 geboren worden. Seit 1990 war im Laufe der Jahre eine ganze Reihe von Massnahmen beschlossen und umgesetzt worden, um die Krankheit bei den Rindern einzudämmen. Es wurde in der Schweiz nie ein Fall der Variante der Creutzfeldt-Jakob-Erkrankung bei Menschen, die mit BSE in Verbindung gebracht wird, diagnostiziert.

Weitere Informationen finden sie auf der Web-Seite des BVET unter www.bvet.admin.ch > BSE. Sie finden dort insbesondere die Geschichte der getroffenen Massnahmen sowie Grafiken zur Entwicklung der BSE-Fälle in der Schweiz.

Adresse für Rückfragen: Regula Kennel, Bundesamt für Veterinärwesen Tel.: 031 323 84 96 Herausgeber: Bundesamt für VeterinärwesenInternet: http://www.bvet.admin.ch

Volltextsuche Suche

erweiterte Suche

Die Bundesbehörden der Schweizerischen Eidgenossenschaft webmaster@admin.ch | Rechtliche Grundlagen


http://www.news.admin.ch/message/index.html?lang=de&msg-id=43728






also, atypical bse and feed IS A FACTOR !


amplification and transmission of atypical BSE via feed is real, and can transmit just like the typical BSE did. any other statement is NOT based on science, but on TRADE $$$




P.9.21

Molecular characterization of BSE in Canada

Jianmin Yang1, Sandor Dudas2, Catherine Graham2, Markus Czub3, Tim McAllister1, Stefanie Czub1 1Agriculture and Agri-Food Canada Research Centre, Canada; 2National and OIE BSE Reference Laboratory, Canada; 3University of Calgary, Canada

Background: Three BSE types (classical and two atypical) have been identified on the basis of molecular characteristics of the misfolded protein associated with the disease. To date, each of these three types have been detected in Canadian cattle.

Objectives: This study was conducted to further characterize the 16 Canadian BSE cases based on the biochemical properties of there associated PrPres. Methods: Immuno-reactivity, molecular weight, glycoform profiles and relative proteinase K sensitivity of the PrPres from each of the 16 confirmed Canadian BSE cases was determined using modified Western blot analysis.

Results: Fourteen of the 16 Canadian BSE cases were C type, 1 was H type and 1 was L type. The Canadian H and L-type BSE cases exhibited size shifts and changes in glycosylation similar to other atypical BSE cases. PK digestion under mild and stringent conditions revealed a reduced protease resistance of the atypical cases compared to the C-type cases. N terminal- specific antibodies bound to PrPres from H type but not from C or L type. The C-terminal-specific antibodies resulted in a shift in the glycoform profile and detected a fourth band in the Canadian H-type BSE.

Discussion: The C, L and H type BSE cases in Canada exhibit molecular characteristics similar to those described for classical and atypical BSE cases from Europe and Japan. This supports the theory that the importation of BSE contaminated feedstuff is the source of C-type BSE in Canada.

*** It also suggests a similar cause or source for atypical BSE in these countries.



http://www.prion2009.com/sites/default/files/Prion2009_Book_of_Abstracts.pdf







Wednesday, March 7, 2012


The epidemiology of bovine spongiform encephalopathy in the Republic of Ireland before and after the reinforced feed ban


http://madcowfeed.blogspot.com/2012/03/epidemiology-of-bovine-spongiform.html







Wednesday, March 7, 2012


Case-control study of cases of bovine spongiform encephalopathy born after July 31, 1996 (BARB cases) in Great Britain


Veterinary Record doi:10.1136/vr.100097


http://madcowfeed.blogspot.com/2012/03/case-control-study-of-cases-of-bovine.html










Thursday, February 16, 2012

Bovine Spongiform Encephalopathy BSE

31 USA SENATORS ASK PRESIDENT OBAMA TO HELP SPREAD MAD COW DISEASE 2012


http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/bovine-spongiform-encephalopathy-bse-31.html





Thursday, February 23, 2012

EIGHT FORMER SECRETARIES OF AGRICULTURE SPEAKING AT USDA'S 2012 AGRICULTURE OUTLOOK FORUM INDUCTED INTO USA MAD COW HALL OF SHAME


http://madcowusda.blogspot.com/2012/02/eight-former-secretaries-of-agriculture.html






Sunday, February 5, 2012 February 2012

Update on Feed Enforcement Activities to Limit the Spread of BSE


http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/february-2012-update-on-feed.html








10,000,000+ LBS. of PROHIBITED BANNED MAD COW FEED I.E. BLOOD LACED MBM IN COMMERCE USA 2007

Date: March 21, 2007 at 2:27 pm PST

RECALLS AND FIELD CORRECTIONS: VETERINARY MEDICINES -- CLASS II

___________________________________

PRODUCT

Bulk cattle feed made with recalled Darling's 85% Blood Meal, Flash Dried, Recall # V-024-2007

CODE

Cattle feed delivered between 01/12/2007 and 01/26/2007

RECALLING FIRM/MANUFACTURER

Pfeiffer, Arno, Inc, Greenbush, WI. by conversation on February 5, 2007.

Firm initiated recall is ongoing.

REASON

Blood meal used to make cattle feed was recalled because it was cross- contaminated with prohibited bovine meat and bone meal that had been manufactured on common equipment and labeling did not bear cautionary BSE statement.

VOLUME OF PRODUCT IN COMMERCE

42,090 lbs.

DISTRIBUTION

WI

___________________________________

PRODUCT

Custom dairy premix products: MNM ALL PURPOSE Pellet, HILLSIDE/CDL Prot- Buffer Meal, LEE, M.-CLOSE UP PX Pellet, HIGH DESERT/ GHC LACT Meal, TATARKA, M CUST PROT Meal, SUNRIDGE/CDL PROTEIN Blend, LOURENZO, K PVM DAIRY Meal, DOUBLE B DAIRY/GHC LAC Mineral, WEST PIONT/GHC CLOSEUP Mineral, WEST POINT/GHC LACT Meal, JENKS, J/COMPASS PROTEIN Meal, COPPINI - 8# SPECIAL DAIRY Mix, GULICK, L-LACT Meal (Bulk), TRIPLE J - PROTEIN/LACTATION, ROCK CREEK/GHC MILK Mineral, BETTENCOURT/GHC S.SIDE MK-MN, BETTENCOURT #1/GHC MILK MINR, V&C DAIRY/GHC LACT Meal, VEENSTRA, F/GHC LACT Meal, SMUTNY, A- BYPASS ML W/SMARTA, Recall # V-025-2007

CODE

The firm does not utilize a code - only shipping documentation with commodity and weights identified.

RECALLING FIRM/MANUFACTURER

Rangen, Inc, Buhl, ID, by letters on February 13 and 14, 2007. Firm initiated recall is complete.

REASON

Products manufactured from bulk feed containing blood meal that was cross contaminated with prohibited meat and bone meal and the labeling did not bear cautionary BSE statement.

VOLUME OF PRODUCT IN COMMERCE

9,997,976 lbs.

DISTRIBUTION

ID and NV

END OF ENFORCEMENT REPORT FOR MARCH 21, 2007

http://www.fda.gov/bbs/topics/enforce/2007/ENF00996.html




NEW URL

http://www.fda.gov/Safety/Recalls/EnforcementReports/2007/ucm120446.htm






Thursday, March 19, 2009

MILLIONS AND MILLIONS OF POUNDS OF MAD COW FEED IN COMMERCE USA WITH ONGOING 12 YEARS OF DENIAL

http://madcowfeed.blogspot.com/2009/03/millions-and-millions-of-pounds-of-mad.html







Tuesday, March 2, 2010

Animal Proteins Prohibited in Ruminant Feed/Adulterated/Misbranded Rangen Inc 2/11/10 USA

http://madcowfeed.blogspot.com/2010/03/animal-proteins-prohibited-in-ruminant.html







Monday, March 1, 2010

ANIMAL PROTEIN I.E. MAD COW FEED IN COMMERCE A REVIEW 2010

http://madcowfeed.blogspot.com/2010/03/animal-protien-ie-mad-cow-feed-in.html











THANKS to the OIE and the USDA, and the BSE MRR policy, the legal trading of all strains of mad cow disease, more cases like this will come. ...TSS



Saturday, November 19, 2011

Novel Prion Protein in BSE-affected Cattle, Switzerland

http://transmissiblespongiformencephalopathy.blogspot.com/2011/11/novel-prion-protein-in-bse-affected.html





Friday, December 23, 2011

Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model

Volume 18, Number 1—January 2012 Dispatch

http://transmissiblespongiformencephalopathy.blogspot.com/2011/12/oral-transmission-of-l-type-bovine.html





Monday, October 10, 2011

EFSA Journal 2011 The European Response to BSE: A Success Story

snip...

EFSA and the European Centre for Disease Prevention and Control (ECDC) recently delivered a scientific opinion on any possible epidemiological or molecular association between TSEs in animals and humans (EFSA Panel on Biological Hazards (BIOHAZ) and ECDC, 2011). This opinion confirmed Classical BSE prions as the only TSE agents demonstrated to be zoonotic so far but the possibility that a small proportion of human cases so far classified as "sporadic" CJD are of zoonotic origin could not be excluded. Moreover, transmission experiments to non-human primates suggest that some TSE agents in addition to Classical BSE prions in cattle (namely L-type Atypical BSE, Classical BSE in sheep, transmissible mink encephalopathy (TME) and chronic wasting disease (CWD) agents) might have zoonotic potential.

snip...


http://www.efsa.europa.eu/en/efsajournal/pub/e991.htm?emt=1





http://www.efsa.europa.eu/en/efsajournal/doc/e991.pdf





see follow-up here about North America BSE Mad Cow TSE prion risk factors, and the ever emerging strains of Transmissible Spongiform Encephalopathy in many species here in the USA, including humans ;


http://transmissiblespongiformencephalopathy.blogspot.com/2011/10/efsa-journal-2011-european-response-to.html





Thursday, August 12, 2010

Seven main threats for the future linked to prions

First threat

The TSE road map defining the evolution of European policy for protection against prion diseases is based on a certain numbers of hypotheses some of which may turn out to be erroneous. In particular, a form of BSE (called atypical Bovine Spongiform Encephalopathy), recently identified by systematic testing in aged cattle without clinical signs, may be the origin of classical BSE and thus potentially constitute a reservoir, which may be impossible to eradicate if a sporadic origin is confirmed.

***Also, a link is suspected between atypical BSE and some apparently sporadic cases of Creutzfeldt-Jakob disease in humans. These atypical BSE cases constitute an unforeseen first threat that could sharply modify the European approach to prion diseases.

Second threat

snip...


http://www.neuroprion.org/en/np-neuroprion.html







Saturday, June 25, 2011

Transmissibility of BSE-L and Cattle-Adapted TME Prion Strain to Cynomolgus Macaque

"BSE-L in North America may have existed for decades"


http://transmissiblespongiformencephalopathy.blogspot.com/2011/06/transmissibility-of-bse-l-and-cattle.html





Over the next 8-10 weeks, approximately 40% of all the adult mink on the farm died from TME.

snip...

The rancher was a ''dead stock'' feeder using mostly (>95%) downer or dead dairy cattle...


http://web.archive.org/web/20030516051623/http://www.bseinquiry.gov.uk/files/mb/m09/tab05.pdf





Sunday, February 5, 2012

February 2012 Update on Feed Enforcement Activities to Limit the Spread of BSE

http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/february-2012-update-on-feed.html





Saturday, March 5, 2011

MAD COW ATYPICAL CJD PRION TSE CASES WITH CLASSIFICATIONS PENDING ON THE RISE IN NORTH AMERICA

http://transmissiblespongiformencephalopathy.blogspot.com/2011/03/mad-cow-atypical-cjd-prion-tse-cases.html





Sunday, February 12, 2012

National Prion Disease Pathology Surveillance Center Cases Examined1 (August 19, 2011) including Texas

http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/national-prion-disease-pathology.html





Friday, March 09, 2012

Experimental H-type and L-type bovine spongiform encephalopathy in cattle: observation of two clinical syndromes and diagnostic challenges

Research article

http://bse-atypical.blogspot.com/2012/03/experimental-h-type-and-l-type-bovine.html





USDA OIE ON HOW TO TRADE MAD COW DISEASE GLOBALLY $$$


Sunday, March 11, 2012

APHIS Proposes New Bovine Spongiform Encephalopathy Import Regulations in Line with International Animal Health Standards Proposal Aims to Ensure Health of the U.S. Beef Herd, Assist in Negotiations

http://transmissiblespongiformencephalopathy.blogspot.com/2012/03/aphis-proposes-new-bovine-spongiform.html






Saturday, February 14, 2009

A case-control study of sporadic Creutzfeldt-Jakob disease in Switzerland: analysis of potential risk factors with regard to an increased CJD incidence in the years 2001–2004


http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=2637857&blobtype=pdf






>>>The rise in annual mortality rate from the years before 2000 to the period 2001– 2004, however, was statistically significant, and therefore, chance must be considered a less likely explanation.<<<




SEE FULL TEXT AND MORE HERE ;


http://creutzfeldt-jakob-disease.blogspot.com/2009/02/case-control-study-of-sporadic.html





Saturday, March 5, 2011

MAD COW ATYPICAL CJD PRION TSE CASES WITH CLASSIFICATIONS PENDING ON THE RISE IN NORTH AMERICA

http://transmissiblespongiformencephalopathy.blogspot.com/2011/03/mad-cow-atypical-cjd-prion-tse-cases.html



Sunday, February 12, 2012

National Prion Disease Pathology Surveillance Center Cases Examined1 (August 19, 2011) including Texas

http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/national-prion-disease-pathology.html




Tuesday, February 28, 2012

The 27th Colloque Médecine et Recherche of the Fondation Ipsen in the Alzheimer Disease series: “Proteopathic Seeds and Neurodegenerative Diseases”

Press release

http://betaamyloidcjd.blogspot.com/2012/02/27th-colloque-medecine-et-recherche-of.html





TSS

Another cow enters food supply without being tested for BSE aka mad cow disease UK 15 March 2012

Cow aged over 72 months enters food supply without being tested for BSE



Thursday 15 March 2012


The Agency has been notified that meat has entered the food supply from a cow aged over 72 months that had not been tested for BSE. A negative BSE test result is mandatory for cattle slaughtered for human consumption at over 72 months of age.

It is very unlikely that the cow was infected with BSE and, as specified risk material (SRM) was removed, any risk to human health is extremely low. SRM is the parts of cattle most likely to carry BSE infectivity.

The cow, aged 158 months and 22 days, was slaughtered at Rhinds of Elgin Ltd abattoir in Moray, Scotland, on 10 January 2012. The error was discovered on 28 February in the course of routine cross-checks of slaughter and BSE test data.

According to BSE regulations, the untested cow, plus the one slaughtered before and the two, after should not have entered the food supply. However, by the time the failure was discovered, the associated carcasses had left the premises.

Some frozen offal and meat product directly linked to these carcasses has since been destroyed. However, checks found that most the meat from these carcasses is likely to have been eaten.

Individual reports of BSE controls breaches 2012


http://www.food.gov.uk/news/newsarchive/2012/mar/605602




Wednesday, March 7, 2012

ANOTHER COW NOT TESTED FOR BSE AKA MAD COW LIKELY TO HAVE BEEN EATEN UK 2012

http://madcowtesting.blogspot.com/2012/03/another-cow-not-tested-for-bse-aka-mad.html





Sunday, March 11, 2012

APHIS Proposes New Bovine Spongiform Encephalopathy Import Regulations in Line with International Animal Health Standards Proposal Aims to Ensure Health of the U.S. Beef Herd, Assist in Negotiations


http://transmissiblespongiformencephalopathy.blogspot.com/2012/03/aphis-proposes-new-bovine-spongiform.html






Thursday, March 01, 2012

Variant Creutzfeldt-Jakob disease Fact sheet N°180 Revised February 2012 W.H.O.

http://vcjd.blogspot.com/2012/03/variant-creutzfeldt-jakob-disease-fact.html





SNIP...

WHO response

WHO has worked on: convening scientific consultations on issues related to animal and human TSEs (these meetings have made recommendations aimed at protecting human and animal health); assisting with global surveillance of CJD and its variants, by holding training courses worldwide, particularly in developing countries, to help countries establish national surveillance of CJD and its variants; convening the Technical Consultation on BSE: Public Health, Animal Health and Trade, publishing the WHO manual for surveillance of human transmissible spongiform encephalopathies, including variant Creutzfeldt-Jakob disease. WHO recommendations




To protect human health, WHO has several recommendations. No tissue that is likely to contain the BSE agent, nor part or product of any animal which has shown signs of a TSE should enter the (human or animal) food chain. All countries should ban the use of ruminant tissues in ruminant feed. The pharmaceutical industry should avoid the use of bovine materials and materials from other animal species in which TSEs naturally occur. If their use is absolutely necessary, these materials should be obtained from countries which have a surveillance system for BSE in place and which reports zero cases of BSE. The Guidelines on tissue infectivity distribution in transmissible spongiform encephalopathies in 2006 provide information and assist national regulatory authorities in conducting risk assessments of vCJD transmission. In 2010, WHO updated the Tables on tissue infectivity distribution in transmissible spongiform encephalopathies. The Tables reflect the current status of knowledge about infectivity in body tissues, secretions, and excretions of humans and animals, and thus provide information about potential transmission of vCJD through human blood and blood products, as well as through medicinal products prepared with animal-derived materials.




--------------------------------------------------------------------------------




1 The term "Classical BSE" has been introduced to differentiate the disease from Atypical BSE cases, which occur rarely in the cattle population.




http://www.who.int/mediacentre/factsheets/fs180/en/




WHO Tables on Tissue Infectivity Distribution in Transmissible Spongiform Encephalopathies Updated 2010




http://www.who.int/bloodproducts/tablestissueinfectivity.pdf






Key facts missed ;



Monday, October 10, 2011



EFSA Journal 2011 The European Response to BSE: A Success Story

snip...

EFSA and the European Centre for Disease Prevention and Control (ECDC) recently delivered a scientific opinion on any possible epidemiological or molecular association between TSEs in animals and humans (EFSA Panel on Biological Hazards (BIOHAZ) and ECDC, 2011). This opinion confirmed Classical BSE prions as the only TSE agents demonstrated to be zoonotic so far but the possibility that a small proportion of human cases so far classified as "sporadic" CJD are of zoonotic origin could not be excluded. Moreover, transmission experiments to non-human primates suggest that some TSE agents in addition to Classical BSE prions in cattle (namely L-type Atypical BSE, Classical BSE in sheep, transmissible mink encephalopathy (TME) and chronic wasting disease (CWD) agents) might have zoonotic potential.

snip...

http://www.efsa.europa.eu/en/efsajournal/pub/e991.htm?emt=1




http://www.efsa.europa.eu/en/efsajournal/doc/e991.pdf






see follow-up here about North America BSE Mad Cow TSE prion risk factors, and the ever emerging strains of Transmissible Spongiform Encephalopathy in many species here in the USA, including humans ;




http://transmissiblespongiformencephalopathy.blogspot.com/2011/10/efsa-journal-2011-european-response-to.html






Thursday, August 12, 2010

Seven main threats for the future linked to prions

First threat

The TSE road map defining the evolution of European policy for protection against prion diseases is based on a certain numbers of hypotheses some of which may turn out to be erroneous. In particular, a form of BSE (called atypical Bovine Spongiform Encephalopathy), recently identified by systematic testing in aged cattle without clinical signs, may be the origin of classical BSE and thus potentially constitute a reservoir, which may be impossible to eradicate if a sporadic origin is confirmed.

***Also, a link is suspected between atypical BSE and some apparently sporadic cases of Creutzfeldt-Jakob disease in humans. These atypical BSE cases constitute an unforeseen first threat that could sharply modify the European approach to prion diseases.

Second threat

snip...




http://www.neuroprion.org/en/np-neuroprion.html






Atypical BSE in Cattle




To date the OIE/WAHO assumes that the human and animal health standards set out in the BSE chapter for classical BSE (C-Type) applies to all forms of BSE which include the H-type and L-type atypical forms. This assumption is scientifically not completely justified and accumulating evidence suggests that this may in fact not be the case. Molecular characterization and the spatial distribution pattern of histopathologic lesions and immunohistochemistry (IHC) signals are used to identify and characterize atypical BSE. Both the L-type and H-type atypical cases display significant differences in the conformation and spatial accumulation of the disease associated prion protein (PrPSc) in brains of afflicted cattle. Transmission studies in bovine transgenic and wild type mouse models support that the atypical BSE types might be unique strains because they have different incubation times and lesion profiles when compared to C-type BSE. When L-type BSE was inoculated into ovine transgenic mice and Syrian hamster the resulting molecular fingerprint had changed, either in the first or a subsequent passage, from L-type into C-type BSE.




In addition, non-human primates are specifically susceptible for atypical BSE as demonstrated by an approximately 50% shortened incubation time for L-type BSE as compared to C-type. Considering the current scientific information available, it cannot be assumed that these different BSE types pose the same human health risks as C-type BSE or that these risks are mitigated by the same protective measures.





This study will contribute to a correct definition of specified risk material (SRM) in atypical BSE. The incumbent of this position will develop new and transfer existing, ultra-sensitive methods for the detection of atypical BSE in tissue of experimentally infected cattle.



http://www.prionetcanada.ca/detail.aspx?menu=5&dt=293380&app=93&cat1=387&tp=20&lk=no&cat2





When L-type BSE was inoculated into ovine transgenic mice and Syrian hamster the resulting molecular fingerprint had changed, either in the first or a subsequent passage, from L-type into C-type BSE. In addition, non-human primates are specifically susceptible for atypical BSE as demonstrated by an approximately 50% shortened incubation time for L-type BSE as compared to C-type. Considering the current scientific information available, it cannot be assumed that these different BSE types pose the same human health risks as C-type BSE or that these risks are mitigated by the same protective measures.




This study will contribute to a correct definition of specified risk material (SRM) in atypical BSE. The incumbent of this position will develop new and transfer existing, ultra-sensitive methods for the detection of atypical BSE in tissue of experimentally infected cattle.




http://www.prionetcanada.ca/detail.aspx?menu=5&dt=293380&app=93&cat1=387&tp=20&lk=no&cat2





Saturday, June 25, 2011



Transmissibility of BSE-L and Cattle-Adapted TME Prion Strain to Cynomolgus Macaque




"BSE-L in North America may have existed for decades"



http://transmissiblespongiformencephalopathy.blogspot.com/2011/06/transmissibility-of-bse-l-and-cattle.html





Over the next 8-10 weeks, approximately 40% of all the adult mink on the farm died from TME.




snip...




The rancher was a ''dead stock'' feeder using mostly (>95%) downer or dead dairy cattle...




http://web.archive.org/web/20030516051623/http://www.bseinquiry.gov.uk/files/mb/m09/tab05.pdf





Sunday, February 5, 2012



February 2012 Update on Feed Enforcement Activities to Limit the Spread of BSE



http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/february-2012-update-on-feed.html






snip... see more here ;





Thursday, March 01, 2012

Variant Creutzfeldt-Jakob disease Fact sheet N°180 Revised February 2012 W.H.O.



http://vcjd.blogspot.com/2012/03/variant-creutzfeldt-jakob-disease-fact.html






Friday, March 09, 2012




Experimental H-type and L-type bovine spongiform encephalopathy in cattle: observation of two clinical syndromes and diagnostic challenges




Research article




http://bse-atypical.blogspot.com/2012/03/experimental-h-type-and-l-type-bovine.html





2009 UPDATE ON ALABAMA AND TEXAS MAD COWS 2005 and 2006




http://bse-atypical.blogspot.com/2006/08/bse-atypical-texas-and-alabama-update.html




LET'S take a closer look at this new prionpathy or prionopathy, and then let's look at the g-h-BSEalabama mad cow.



This new prionopathy in humans?



the genetic makeup is IDENTICAL to the g-h-BSEalabama mad cow, the only _documented_ mad cow in the world to date like this, ......wait, it get's better. this new prionpathy is killing young and old humans, with LONG DURATION from onset of symptoms to death, and the symptoms are very similar to nvCJD victims, OH, and the plaques are very similar in some cases too, bbbut, it's not related to the g-h-BSEalabama cow, WAIT NOW, it gets even better, the new human prionpathy that they claim is a genetic TSE, has no relation to any gene mutation in that family. daaa, ya think it could be related to that mad cow with the same genetic make-up ???



there were literally tons and tons of banned mad cow protein in Alabama in commerce, and none of it transmitted to cows, and the cows to humans there from ??? r i g h t $$$





ALABAMA MAD COW g-h-BSEalabama In this study, we identified a novel mutation in the bovine prion protein gene (Prnp), called E211K, of a confirmed BSE positive cow from Alabama, United States of America. This mutation is identical to the E200K pathogenic mutation found in humans with a genetic form of CJD. This finding represents the first report of a confirmed case of BSE with a potential pathogenic mutation within the bovine Prnp gene. We hypothesize that the bovine Prnp E211K mutation most likely has caused BSE in "the approximately 10-year-old cow" carrying the E221K mutation.


http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1000156




http://www.plospathogens.org/article/fetchObjectAttachment.action?uri=info%3Adoi%2F10.1371%2Fjournal.ppat.1000156&representation=PDF






Saturday, August 14, 2010




BSE Case Associated with Prion Protein Gene Mutation (g-h-BSEalabama) and VPSPr PRIONPATHY (see mad cow feed in COMMERCE IN ALABAMA...TSS)


http://prionpathy.blogspot.com/2010/08/bse-case-associated-with-prion-protein.html





her healthy calf also carried the mutation (J. A. Richt and S. M. Hall PLoS Pathog. 4, e1000156; 2008).




This raises the possibility that the disease could occasionally be genetic in origin. Indeed, the report of the UK BSE Inquiry in 2000 suggested that the UK epidemic had most likely originated from such a mutation and argued against the scrapierelated assumption. Such rare potential pathogenic PRNP mutations could occur in countries at present considered to be free of BSE, such as Australia and New Zealand. So it is important to maintain strict surveillance for BSE in cattle, with rigorous enforcement of the ruminant feed ban (many countries still feed ruminant proteins to pigs). Removal of specified risk material, such as brain and spinal cord, from cattle at slaughter prevents infected material from entering the human food chain. Routine genetic screening of cattle for PRNP mutations, which is now available, could provide additional data on the risk to the public. Because the point mutation identified in the Alabama animals is identical to that responsible for the commonest type of familial (genetic) CJD in humans, it is possible that the resulting infective prion protein might cross the bovine-human species barrier more easily. Patients with vCJD continue to be identified. The fact that this is happening less often should not lead to relaxation of the controls necessary to prevent future outbreaks. Malcolm A. Ferguson-Smith Cambridge University Department of Veterinary Medicine, Madingley Road, Cambridge CB3 0ES, UK e-mail: maf12@cam.ac.uk Jürgen A. Richt College of Veterinary Medicine, Kansas State University, K224B Mosier Hall, Manhattan, Kansas 66506-5601, USA NATURE|Vol 457|26 February 2009




http://www.nature.com/nature/journal/v457/n7233/full/4571079b.html





P.9.21 Molecular characterization of BSE in Canada



Jianmin Yang1, Sandor Dudas2, Catherine Graham2, Markus Czub3, Tim McAllister1, Stefanie Czub1 1Agriculture and Agri-Food Canada Research Centre, Canada; 2National and OIE BSE Reference Laboratory, Canada; 3University of Calgary, Canada




Background: Three BSE types (classical and two atypical) have been identified on the basis of molecular characteristics of the misfolded protein associated with the disease. To date, each of these three types have been detected in Canadian cattle.




Objectives: This study was conducted to further characterize the 16 Canadian BSE cases based on the biochemical properties of there associated PrPres.




Methods: Immuno-reactivity, molecular weight, glycoform profiles and relative proteinase K sensitivity of the PrPres from each of the 16 confirmed Canadian BSE cases was determined using modified Western blot analysis. Results: Fourteen of the 16 Canadian BSE cases were C type, 1 was H type and 1 was L type. The Canadian H and L-type BSE cases exhibited size shifts and changes in glycosylation similar to other atypical BSE cases. PK digestion under mild and stringent conditions revealed a reduced protease resistance of the atypical cases compared to the C-type cases. N terminal- specific antibodies bound to PrPres from H type but not from C or L type. The C-terminal-specific antibodies resulted in a shift in the glycoform profile and detected a fourth band in the Canadian H-type BSE.




Discussion: The C, L and H type BSE cases in Canada exhibit molecular characteristics similar to those described for classical and atypical BSE cases from Europe and Japan. This supports the theory that the importation of BSE contaminated feedstuff is the source of C-type BSE in Canada. *** It also suggests a similar cause or source for atypical BSE in these countries.




http://www.prion2009.com/sites/default/files/Prion2009_Book_of_Abstracts.pdf





Saturday, July 23, 2011




CATTLE HEADS WITH TONSILS, BEEF TONGUES, SPINAL CORD, SPECIFIED RISK MATERIALS (SRM's) AND PRIONS, AKA MAD COW DISEASE




http://transmissiblespongiformencephalopathy.blogspot.com/2011/07/cattle-heads-with-tonsils-beef-tongues.html






Saturday, November 6, 2010




TAFS1 Position Paper on Position Paper on Relaxation of the Feed Ban in the EU




Berne, 2010 TAFS INTERNATIONAL FORUM FOR TRANSMISSIBLE ANIMAL DISEASES AND FOOD SAFETY a non-profit Swiss Foundation


http://madcowfeed.blogspot.com/2010/11/tafs1-position-paper-on-position-paper.html





Archive Number 20101206.4364 Published Date 06-DEC-2010 Subject PRO/AH/EDR>




Prion disease update 2010 (11) PRION DISEASE UPDATE 2010 (11)




http://www.promedmail.org/direct.php?id=20101206.4364






October 2009 O.11.3 Infectivity in skeletal muscle of BASE-infected cattle

Silvia Suardi1, Chiara Vimercati1, Fabio Moda1, Ruggerone Margherita1, Ilaria Campagnani1, Guerino Lombardi2, Daniela Gelmetti2, Martin H. Groschup3, Anne Buschmann3, Cristina Casalone4, Maria Caramelli4, Salvatore Monaco5, Gianluigi Zanusso5, Fabrizio Tagliavini1 1Carlo Besta" Neurological Institute,Italy; 2IZS Brescia, Italy; 33FLI Insel Riems, D, Germany; 4CEA-IZS Torino, Italy; 5University of Verona, Italy




Background: BASE is an atypical form of bovine spongiform encephalopathy caused by a prion strain distinct from that of BSE. Upon experimental transmission to cattle, BASE induces a previously unrecognized disease phenotype marked by mental dullness and progressive atrophy of hind limb musculature. Whether affected muscles contain infectivity is unknown. This is a critical issue since the BASE strain is readily transmissible to a variety of hosts including primates, suggesting that humans may be susceptible.




Objectives: To investigate the distribution of infectivity in peripheral tissues of cattle experimentally infected with BASE. Methods: Groups of Tg mice expressing bovine PrP (Tgbov XV, n= 7-15/group) were inoculated both i.c. and i.p. with 10% homogenates of a variety of tissues including brain, spleen, cervical lymph node, kidney and skeletal muscle (m. longissimus dorsi) from cattle intracerebrally infected with BASE. No PrPres was detectable in the peripheral tissues used for inoculation either by immunohistochemistry or Western blot.




Results: Mice inoculated with BASE-brain homogenates showed clinical signs of disease with incubation and survival times of 175±15 and 207±12 days. Five out of seven mice challenged with skeletal muscle developed a similar neurological disorder, with incubation and survival times of 380±11 and 410±12 days. At present (700 days after inoculation) mice challenged with the other peripheral tissues are still healthy. The neuropathological phenotype and PrPres type of the affected mice inoculated either with brain or muscle were indistinguishable and matched those of Tgbov XV mice infected with natural BASE.




Discussion: Our data indicate that the skeletal muscle of cattle experimentally infected with BASE contains significant amount of infectivity, at variance with BSE-affected cattle, raising the issue of intraspecies transmission and the potential risk for humans. Experiments are in progress to assess the presence of infectivity in skeletal muscles of natural BASE.


http://www.prion2009.com/sites/default/files/Prion2009_Book_of_Abstracts.pdf





Saturday, March 5, 2011




MAD COW ATYPICAL CJD PRION TSE CASES WITH CLASSIFICATIONS PENDING ON THE RISE IN NORTH AMERICA




http://transmissiblespongiformencephalopathy.blogspot.com/2011/03/mad-cow-atypical-cjd-prion-tse-cases.html






Sunday, February 12, 2012




National Prion Disease Pathology Surveillance Center Cases Examined1 (August 19, 2011) including Texas




http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/national-prion-disease-pathology.html





Tuesday, February 28, 2012




The 27th Colloque Médecine et Recherche of the Fondation Ipsen in the Alzheimer Disease series: “Proteopathic Seeds and Neurodegenerative Diseases”




Press release



http://betaamyloidcjd.blogspot.com/2012/02/27th-colloque-medecine-et-recherche-of.html





TSS

APHIS Proposes New Bovine Spongiform Encephalopathy Import Regulations in Line with International Animal Health Standards Proposal Aims to Ensure Health of the U.S. Beef Herd, Assist in Negotiations

APHIS Proposes New Bovine Spongiform Encephalopathy Import Regulations in Line with International Animal Health Standards Proposal Aims to Ensure Health of the U.S. Beef Herd, Assist in Negotiations
Abby Yigzaw (301)851-4096 Lyndsay Cole (970) 494-7410

APHIS Proposes New Bovine Import Regulations in Line with International Animal Health Standards Proposal Aims to Ensure Health of the U.S. Beef Herd, Assist in Negotiations

WASHINGTON, March 9, 2012--The U.S. Department of Agriculture’s (USDA) Animal and Plant Health Inspection Service (APHIS) announced today it is seeking public review and comment on a proposal to complete efforts to modernize the Agency’s import regulations for bovine spongiform encephalopathy (BSE).

“This proposal is an important step forward in our efforts to bring our import regulations in line with science-based, international animal health standards,” said Dr. John Clifford, APHIS Deputy Administrator and Chief Veterinary Officer. “The proposal will help ensure we continue to provide strong protections against BSE, continue to make science-based decisions, and fully support safe trade in bovine commodities. As we continue to protect the health of the U.S. cattle industry, this proposal will also assist us in future negotiations to reopen important trade markets that remain closed to U.S. beef.”

While the proposed rule would allow for the safe trade of additional bovines and bovine products, it’s important to note that control of imports is only one of several interlocking safeguards against BSE. The proposed rule would not change other measures that are currently in place in the United States. For animal health, these measures include the U.S. Food and Drug Administration's ruminant-to-ruminant feed ban and a robust BSE surveillance program. Human health is protected by measures that ensure the safety of U.S. beef, the most important of which is the ban on animal materials that have been shown to carry the BSE agent (known as specified risk materials) from the food supply.

Under the proposed rule, APHIS would adopt the same criteria and categories that the World Organization for Animal Health (OIE) uses to identify a country’s BSE risk status—negligible, controlled, and undetermined risk. APHIS would base its import policy for a particular country on that country’s risk classification as determined by OIE’s risk evaluation. The rule would also allow APHIS to conduct its own assessment when deemed necessary, such as when a country is not yet classified by the OIE for BSE risk and requests that APHIS conduct a risk evaluation using criteria equivalent to that used by OIE. All countries would be considered by APHIS to have an undetermined BSE risk unless officially recognized as either negligible or controlled risk.

The OIE determines a country’s risk status based on actions the country has taken to manage the risk of the disease. These actions include instituting a strong ruminant-to-ruminant feed ban, strictly controlling imports of animals and animal products from countries of undetermined risk, and conducting appropriate surveillance.

The OIE Code, which is based on the latest science and current knowledge concerning BSE, provides guidelines for the safe trade of animals and products based on the country’s risk status and the risk presented by the specific item being traded. For example, under the Code, boneless beef is considered to be lower risk and could be safely imported regardless of the BSE status of the exporting country. Live animals, however, present a higher risk and the OIE guidelines recommend that import requirements be applied depending on the BSE risk classification of the exporting country. In the United States, imported commodities would also need to meet entry requirements for other diseases, where applicable.

This action is scheduled for publication in the Federal Register within a week. The proposed rule is currently available at www.aphis.usda.gov.

Consideration will be given to comments received within 60 days of the rule’s publication in the Federal Register. Send two copies of postal mail or commercial delivery comments to Docket No. APHIS-2008-0010, Regulatory Analysis and Development, PPD, APHIS, Station 3A-03.8, 4700 River Road, Unit 118, Riverdale, MD 20737-1238. If you wish to submit a comment using the Internet go to the Federal eRulemaking portal at http://www.regulations.gov/ fdmspublic/component/main?main=DocketDetail&d=APHIS-2008-0010. This link will be active upon the rule’s publication in the Federal Register.

Comments are posted on the Reglations.gov website and may also be reviewed at USDA, Room 1141, South Building, 14th St. and Independence Ave., S.W., Washington, DC, between 8 a.m. and 4:30 p.m., Monday through Friday, excluding holidays. To facilitate entry into the comment reading room, please call (202) 690-2817.

Currently, U.S. agriculture is experiencing one of its best period in history thanks to the productivity, resiliency, and resourcefulness of our farmers and ranchers. The work of APHIS helps safeguard our nation’s agriculture, fishing and forestry industries from unwanted pests, disease and unjustified trade restrictions. For example, to promote the health of U.S. agricultural exports, APHIS develops and advances science-based standards with trading partners to ensure our farm exports, valued at more than $137 billion annually, are protected from unjustified barriers. Strong agricultural exports are a positive contribution to the U.S. trade balance, support more than 1 million American jobs and boost economic growth.

#

Note to Reporters: USDA news releases, program announcements, and media advisories are available on the Internet and through Really Simple Syndication (RSS) feeds. Go to the APHIS news release page at www.aphis.usda.gov/newsroom and click on the RSS feed link. ____________ USDA is an equal opportunity provider, employer and lender. To file a complaint of discrimination, write: USDA, Director, Office of Civil Rights, 1400 Independence Avenue, S.W., Washington, D.C. 20250-9410 or call (800) 795-3272 (voice), or (202) 720-6382 (TDD).



http://www.aphis.usda.gov/newsroom/2012/03/bse_rule.shtml






Canada Welcomes US-Proposed Modernized Import Regulations for BSE


March 9, 2012, Ottawa: The Government of Canada welcomes the United States Department of Agriculture (USDA) proposal to modernize its import regulations for bovine spongiform encephalopathy (BSE). The proposed changes are based on World Organisation for Animal Health (OIE) guidelines, which Canada also follows.

“Canada supports today’s announcement as we have always maintained that a science-based approach is the best way to manage BSE,” said Agriculture Minister Ritz. “We know that trade should not be affected when countries such as Canada and the United States put in place appropriate measures to protect human and animal health.”

OIE guidelines allow for live cattle and beef products to be safely traded, provided that countries have taken appropriate steps to manage BSE, such as feed controls and surveillance. This announcement follows Minister Ritz’s trade mission to Washington, D.C. where he raised the importance of trade based on sound science and rules that are in line with the international guidelines of the OIE.

Given the integrated North American cattle market, Canada already enjoys a strong trade relationship with the US. This proposed approach underscores the commitment on both sides of the border to responsibly manage BSE, without placing unnecessary restrictions on trade.

Canada continues to effectively manage BSE through a series of integrated safeguards designed to protect both human and animal health. These include prohibiting risk materials from entering the human food and animal feed chains and testing cattle for BSE.

The USDA is accepting comments on its proposed rule for 60 days. For more information on the proposal, visit the USDA website.

For more information on Canada’s BSE control measures
•call 1-800-442-2342
•visit www.inspection.gc.ca/bse

Media enquiries:

CFIA Media Relations
613-773-6600




http://www.inspection.gc.ca/about-the-cfia/newsroom/news-releases/bse/eng/1331332954198/1331332994593






Greetings USDA, OIE et al,



what a difference it makes with science, from one day to the next. i.e. that mad cow gold card the USA once held. up until that fateful day in December of 2003, the science of BSE was NO IMPORTS TO USA FROM BSE COUNTRY.

what a difference a day makes$ now that the shoe is on the other foot, the USDA via the OIE, wants to change science again, just for trade $

I implore the OIE decision and policy makers, for the sake of the world, to refuse any status quo of the USA BSE risk assessment. if at al, the USA BSE GBR should be raise to BSE GBR IV, for the following reasons.

North America is awash with many different TSE Prion strains, in many different species, and they are mutating and spreading.

IF the OIE, and whatever policy makers, do anything but raise the risk factor for BSE in North America, then I would regard that to be highly suspicious.

IN fact, it would be criminal in my opinion, because the OIE knows this, and to knowingly expose the rest of the world to this dangerous pathogen, would be ‘knowingly’ and ‘willfully’, just for the almighty dollar, once again.

I warned the OIE about all this, including the risk factors for CWD, and the fact that the zoonosis potential was great, way back in 2002.

THE OIE in collaboration with the USDA, made the legal trading of the atypical Nor-98 Scrapie a legal global commodity. yes, thanks to the OIE and the USDA et al, it’s now legal to trade the atypical Nor-98 Scrapie strain all around the globe. IF you let them, they will do the same thing with atypical BSE and CWD (both strains to date). This with science showing that indeed these TSE prion strains are transmissible.

I strenuously urge the OIE et al to refuse any weakening to the USA trade protocols for the BSE TSE prion disease (all strains), and urge them to reclassify the USA with BSE GBR IV risk factor.



SOURCE REFERENCES AS FOLLOWS ;





Wednesday, August 11, 2010

REPORT ON THE INVESTIGATION OF THE SIXTEENTH CASE OF BOVINE SPONGIFORM ENCEPHALOPATHY (BSE) IN CANADA

http://bse-atypical.blogspot.com/2010/08/report-on-investigation-of-sixteenth.html






Thursday, August 19, 2010

REPORT ON THE INVESTIGATION OF THE SEVENTEENTH CASE OF BOVINE SPONGIFORM ENCEPHALOPATHY (BSE) IN CANADA

http://bseusa.blogspot.com/2010/08/report-on-investigation-of-seventeenth.html





Thursday, February 10, 2011

TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHY REPORT UPDATE CANADA FEBRUARY 2011 and how to hide mad cow disease in Canada Current as of: 2011-01-31

http://madcowtesting.blogspot.com/2011/02/transmissible-spongiform-encephalopathy.html





Friday, March 4, 2011


Alberta dairy cow found with mad cow disease

http://transmissiblespongiformencephalopathy.blogspot.com/2011/03/alberta-dairy-cow-found-with-mad-cow.html






Saturday, June 19, 2010


U.S. DENIED UPGRADED BSE STATUS FROM OIE


http://usdameatexport.blogspot.com/2010/06/us-denied-upgraded-bse-status-from-oie.html






Comment from Terry S Singletary Sr

Document ID: APHIS-2006-0041-0006 Document

Type: Public Submission This is comment on Proposed


Rule: Bovine Spongiform Encephalopathy; Minimal-Risk Regions; Importation of Live Bovines and Products Derived From Bovines Docket ID: APHIS-2006-0041



http://www.regulations.gov/#!documentDetail;D=APHIS-2006-0041-0006;oldLink=false





http://docket-aphis-2006-0041.blogspot.com/2008/06/bovine-spongiform-encephalopathy.html





http://docket-aphis-2006-0041.blogspot.com/






Docket No. 03-080-1 -- USDA ISSUES PROPOSED RULE TO ALLOW LIVE ANIMAL


IMPORTS FROM CANADA


https://web01.aphis.usda.gov/BSEcom.nsf/0/b78ba677e2b0c12185256dd300649f9d?OpenDocument&AutoFramed







PLEASE SEE FULL TEXT HERE ;


Docket No. 03-080-1 -- USDA ISSUES PROPOSED RULE TO ALLOW LIVE ANIMAL IMPORTS FROM CANADA


http://madcowfeed.blogspot.com/2008/07/docket-no-03-080-1-usda-issues-proposed.html






-------- Original Message --------

Subject: US SENATOR AND STAN THE MAN SLAM USDA ''DAMNING TESTIMONY''

Date: Wed, 3 Mar 2004 15:15:24 –0600

From: "Terry S. Singeltary Sr." flounder@wt.net

Reply-To: Bovine Spongiform Encephalopathy BSE-L@uni-karlsruhe.de

To: BSE-L@uni-karlsruhe.de



######## Bovine Spongiform Encephalopathy #########


Greetings List members,


damning testimony below. be sure to _first_ open up real player competely, then paste your url in there. this worked best for me.........TSS


US SENATOR AND STAN THE MAN SLAM USDA ''DAMNING TESTIMONY''


Senator Michael Machado from California

''USDA does not know what's going on''.

''USDA is protecting the industry''.

''SHOULD the state of California step in''

Stanley Prusiner

''nobody has ever ask us to comment''

''they don't want us to comment''

''they never ask''

i tried to see Venemon, after Candian cow was discovered with BSE. went to see lyle. after talking with him...

absolute ignorance...

then thought I should see Venemon...

it was clear his entire policy was to get cattle bonless beef prods across the border...

nothing else mattered...


his aids confirmed this...

5 times i tried to see Venemon, never worked...

eventually met with carl rove the political...

he is the one that arranged meeting with Venemon...

just trying to give you a sense of the distance...

healh public safety...

was never contacted...

yes i believe that prions are bad to eat and you can die from them...

END



PLEASE NOTE THESE VIDEOS HAVE BEEN REMOVED FROM THE INTERNET $$$



Dr. Stan bashing Ann Veneman - 3 minutes

http://maddeer.org/video/embedded/08snip.ram



Recall Authority and Mad Cow Disease: Is the Current System Good for Californians?

Tuesday, February 24, 2004

JOINT HEARING

AGRICULTURE AND WATER RESOURCES HEALTH AND HUMAN SERVICES AND SELECT
COMMITTEE ON GOVERNMENT OVERSIGHT - MACHADO, ORTIZ, and SPEIER, Chairs

Choose a RealPlayer video --->

Selected excerpts:

Opening Statement by Senator Michael Machado


http://maddeer.org/video/embedded/machado.html



Elisa Odibashian - Consumers Union


http://maddeer.org/video/embedded/odibashian.html



Anthony Iton - Alemeda County Health


http://maddeer.org/video/embedded/iton.html



USDA's "memorandum of understanding"


http://maddeer.org/video/embedded/usda.html



Dave Louthan - Killed the Mad Cow


http://maddeer.org/video/embedded/louthan.html



Dennis Laycraft - Canadian Cattlemen's Association


http://maddeer.org/video/embedded/laycraft.html



Stanley Prusiner - Discoverer of Prions


http://maddeer.org/video/embedded/prusiner.html



Steven DeArmond - Professor of Neuropathology


http://maddeer.org/video/embedded/dearmond.html



Entire 5 hour hearing - The California Channel


(scroll down to "022404 Senate Info-Hearing")


http://www.calchannel.com/february2004.htm



PLEASE NOTE THIS HEARING IN CALIFORNIA, THE VIDEOS HAVE BEEN REMOVED FROM THE INTERNET IN BOTH THE OFFICIAL, AND UNOFFICIAL WEBSITES I.E. MADDEER.ORG AND CALIFORNIA SENATE SITE WHERE THEY ONCE WERE...TSS



Sunday, November 13, 2011


California BSE mad cow beef recall, QFC, CJD, and dead stock downer livestock


http://transmissiblespongiformencephalopathy.blogspot.com/2011/11/california-bse-mad-cow-beef-recall-qfc.html






Thursday, January 5, 2012


Importation of Whole Cuts of Boneless Beef from Japan [Docket No. 05-004-1] RIN 0579-AB93


Subject: Importation of Whole Cuts of Boneless Beef from Japan [Docket No. 05-004-1] RIN 0579-AB93 TSS SUBMISSION




http://docket-aphis-2006-0041.blogspot.com/2012/01/importation-of-whole-cuts-of-boneless.html







Saturday, April 10, 2010




TOYOTA VS MAD COW DISEASE USA OIE BSE MRR IMPORT AND EXPORT TRADE WARS



http://usdameatexport.blogspot.com/2010/04/toyota-vs-mad-cow-disease-usa-oie-bse.html









HARVARD BSE RISK ASSESSMENT AND REASSESSMENT OF SUPPRESSED HARVARD RISK ASSESSMENT THAT WAS SO FLAWED $$$



http://www.fsis.usda.gov/OPPDE/Comments/2006-0011/2006-0011-1.pdf




http://www.fsis.usda.gov/PDF/BSE_Risk_Assess_Response_Public_Comments.pdf







Docket APHIS-2006-0041 Docket Title Bovine Spongiform Encephalopathy; Minimal-Risk Regions; Importation of Live Bovines and Products Derived from Bovines Commodities Docket Type Rulemaking Document APHIS-2006-0041-0001

Document Title Bovine Spongiform Encephalopathy; Minimal-Risk Regions; Importation of Live Bovines and Products Derived From Bovines


Public Submission APHIS-2006-0041-0028 Public Submission Title Comment from Terry S Singletary Comment 2006-2007



USA AND OIE POISONING GLOBE WITH BSE MRR POLICY THE USA is in a most unique situation, one of unknown circumstances with human and animal TSE. THE USA has the most documented TSE in different species to date, with substrains growing in those species (BSE/BASE in cattle and CWD in deer and elk, there is evidence here with different strains), and we know that sheep scrapie has over 20 strains of the typical scrapie with atypical scrapie documented and also BSE is very likely to have passed to sheep. all of which have been rendered and fed back to animals for human and animal consumption, a frightening scenario. WE do not know the outcome, and to play with human life around the globe with the very likely TSE tainted products from the USA, in my opinion is like playing Russian roulette, of long duration, with potential long and enduring consequences, of which once done, cannot be undone. These are the facts as I have come to know through daily and extensive research of TSE over 9 years, since 12/14/97. I do not pretend to have all the answers, but i do know to continue to believe in the ukbsenvcjd only theory of transmission to humans of only this one strain from only this one TSE from only this one part of the globe, will only lead to further failures, and needless exposure to humans from all strains of TSE, and possibly many more needless deaths from TSE via a multitude of proven routes and sources via many studies with primates and rodents and other species. MY personal belief, since you ask, is that not only the Canadian border, but the USA border, and the Mexican border should be sealed up tighter than a drum for exporting there TSE tainted products, until a validated, 100% sensitive test is available, and all animals for human and animal consumption are tested. all we are doing is the exact same thing the UK did with there mad cow poisoning when they exported it all over the globe, all the while knowing what they were doing. this BSE MRR policy is nothing more than a legal tool to do just exactly what the UK did, thanks to the OIE and GW, it's legal now. and they executed Saddam for poisoning ??? go figure. ...


http://www.regulations.gov/fdmspublic/component/main?main=DocumentDetail&o=09000064801f8151




Docket APHIS-2006-0041 Docket Title Bovine Spongiform Encephalopathy; Minimal-Risk Regions; Importation of Live Bovines and Products Derived from Bovines Commodities Docket Type Rulemaking Document APHIS-2006-0041-0001 Document Title Bovine Spongiform Encephalopathy; Minimal-Risk Regions; Importation of Live Bovines and Products Derived From Bovines Public Submission APHIS-2006-0041-0028.1 Public Submission Title Attachment to Singletary comment January 28, 2007


Greetings APHIS, I would kindly like to submit the following to ;


BSE; MRR; IMPORTATION OF LIVE BOVINES AND PRODUCTS DERIVED FROM BOVINES [Docket No. APHIS-2006-0041] RIN 0579-AC01



http://www.regulations.gov/fdmspublic/ContentViewer?objectId=09000064801f8152&disposition=attachment&contentType=msw8





http://www.fsis.usda.gov/OPPDE/Comments/03-025IFA/03-025IFA-2.pdf






Friday, February 18, 2011



UNITED STATES OF AMERICA VS GALEN J. NIEHUES FAKED MAD COW FEED TEST ON 92 BSE INSPECTION REPORTS FOR APPROXIMATELY 100 CATTLE OPERATIONS ''PLEADS GUILTY"



http://bse-atypical.blogspot.com/2011/02/united-states-of-america-vs-galen-j.html






Wednesday, December 22, 2010




Manitoba veterinarian has been fined $10,000 for falsifying certification documents for U.S. bound cattle and what about mad cow disease ?




http://usdameatexport.blogspot.com/2010/12/manitoba-veterinarian-has-been-fined.html






Owner and Corporation Plead Guilty to Defrauding Bovine Spongiform Encephalopathy (BSE) Surveillance Program


An Arizona meat processing company and its owner pled guilty in February 2007 to charges of theft of Government funds, mail fraud, and wire fraud. The owner and his company defrauded the BSE Surveillance Program when they falsified BSE Surveillance Data Collection Forms and then submitted payment requests to USDA for the services. In addition to the targeted sample population (those cattle that were more than 30 months old or had other risk factors for BSE), the owner submitted to USDA, or caused to be submitted, BSE obex (brain stem) samples from healthy USDA-inspected cattle. As a result, the owner fraudulently received approximately $390,000. Sentencing is scheduled for May 2007.

snip...

Topics that will be covered in ongoing or planned reviews under Goal 1 include:

soundness of BSE maintenance sampling (APHIS),

implementation of Performance-Based Inspection System enhancements for specified risk material (SRM) violations and improved inspection controls over SRMs (FSIS and APHIS),

snip...

The findings and recommendations from these efforts will be covered in future semiannual reports as the relevant audits and investigations are completed.

4 USDA OIG SEMIANNUAL REPORT TO CONGRESS FY 2007 1st Half


http://www.usda.gov/oig/webdocs/sarc070619.pdf





-MORE Office of the United States Attorney District of Arizona FOR IMMEDIATE RELEASE For Information Contact Public Affairs February 16, 2007 WYN HORNBUCKLE Telephone: (602) 514-7625 Cell: (602) 525-2681



CORPORATION AND ITS PRESIDENT PLEAD GUILTY TO DEFRAUDING GOVERNMENTS MAD COW DISEASE SURVEILLANCE PROGRAM


PHOENIX -- Farm Fresh Meats, Inc. and Roland Emerson Farabee, 55, of Maricopa, Arizona, pleaded guilty to stealing $390,000 in government funds, mail fraud and wire fraud, in federal district court in Phoenix. U.S. Attorney Daniel Knauss stated, The integrity of the system that tests for mad cow disease relies upon the honest cooperation of enterprises like Farm Fresh Meats. Without that honest cooperation, consumers both in the U.S. and internationally are at risk. We want to thank the USDAs Office of Inspector General for their continuing efforts to safeguard the public health and enforce the law.” Farm Fresh Meats and Farabee were charged by Information with theft of government funds, mail fraud and wire fraud. According to the Information, on June 7, 2004, Farabee, on behalf of Farm Fresh Meats, signed a contract with the U.S. Department of Agriculture (the USDA Agreement) to collect obex samples from cattle at high risk of mad cow disease (the Targeted Cattle Population). The Targeted Cattle Population consisted of the following cattle: cattle over thirty months of age; nonambulatory cattle; cattle exhibiting signs of central nervous system disorders; cattle exhibiting signs of mad cow disease; and dead cattle. Pursuant to the USDA Agreement, the USDA agreed to pay Farm Fresh Meats $150 per obex sample for collecting obex samples from cattle within the Targeted Cattle Population, and submitting the obex samples to a USDA laboratory for mad cow disease testing. Farm Fresh Meats further agreed to maintain in cold storage the sampled cattle carcasses and heads until the test results were received by Farm Fresh Meats.

Evidence uncovered during the government’s investigation established that Farm Fresh Meats and Farabee submitted samples from cattle outside the Targeted Cattle Population. Specifically, Farm Fresh Meats and Farabee submitted, or caused to be submitted, obex samples from healthy, USDA inspected cattle, in order to steal government moneys.

Evidence collected also demonstrated that Farm Fresh Meats and Farabee failed to maintain cattle carcasses and heads pending test results and falsified corporate books and records to conceal their malfeasance. Such actions, to the extent an obex sample tested positive (fortunately, none did), could have jeopardized the USDAs ability to identify the diseased animal and pinpoint its place of origin. On Wednesday, February 14, 2007, Farm Fresh Meats and Farabee pleaded guilty to stealing government funds and using the mails and wires to effect the scheme. According to their guilty pleas:

(a) Farm Fresh Meats collected, and Farabee directed others to collect, obex samples from cattle outside the Targeted Cattle Population, which were not subject to payment by the USDA;

(b) Farm Fresh Meats 2 and Farabee caused to be submitted payment requests to the USDA knowing that the requests were based on obex samples that were not subject to payment under the USDA Agreement;

(c) Farm Fresh Meats completed and submitted, and Farabee directed others to complete and submit, BSE Surveillance Data Collection Forms to the USDA’s testing laboratory that were false and misleading;

(d) Farm Fresh Meats completed and submitted, and Farabee directed others to complete and submit, BSE Surveillance Submission Forms filed with the USDA that were false and misleading;

(e) Farm Fresh Meats falsified, and Farabee directed others to falsify, internal Farm Fresh Meats documents to conceal the fact that Farm Fresh Meats was seeking and obtaining payment from the USDA for obex samples obtained from cattle outside the Targeted Cattle Population; and

(f) Farm Fresh Meats failed to comply with, and Farabee directed others to fail to comply with, the USDA Agreement by discarding cattle carcasses and heads prior to receiving BSE test results. A conviction for theft of government funds carries a maximum penalty of 10 years imprisonment. Mail fraud and wire fraud convictions carry a maximum penalty of 20 years imprisonment. Convictions for the above referenced violations also carry a maximum fine of $250,000 for individuals and $500,000 for organizations. In determining an actual sentence, Judge Earl H. Carroll will consult the U.S. Sentencing Guidelines, which provide appropriate sentencing ranges. The judge, however, is not bound by those guidelines in determining a sentence.

Sentencing is set before Judge Earl H. Carroll on May 14, 2007. The investigation in this case was conducted by Assistant Special Agent in Charge Alejandro Quintero, United States Department of Agriculture, Office of Inspector General. The prosecution is being handled by Robert Long, Assistant U.S. Attorney, District of Arizona, Phoenix. CASE NUMBER: CR-07-00160-PHX-EHC RELEASE NUMBER: 2007-051(Farabee) # # #


http://www.usdoj.gov/usao/az/press_r...1(Farabee).pdf




----- Original Message -----

From: Terry S. Singeltary Sr.

To: Debra.Beasley@aphis.usda.gov

Sent: Tuesday, November 24, 2009 11:01 AM

Subject: OIE has recently published its proposed animal welfare guidelines for public comment

Greetings USDA/APHIS et al,

I would kindly like to comment on OIE proposed guidelines.

AS I said before, OIE should hang up there jock strap now, since it appears they will buckle every time a country makes some political hay about trade protocol, commodities and futures. IF they are not going to be science based, they should do everyone a favor and dissolve there organization. THE reason most every country around the globe came down with BSE/TSE in their cattle, were due to the failed and flawed BSE/TSE testing and surveillance policy of the O.I.E. NOW, they don't even acknowledge atypical scrapie it seems, as one for concern $



Monday, November 23, 2009

BSE GBR RISK ASSESSMENTS UPDATE NOVEMBER 23, 2009 COMMISSION OF THE EUROPEAN COMMUNITIES AND O.I.E.

http://docket-aphis-2006-0041.blogspot.com/2009/11/bse-gbr-risk-assessments-update.html





Tuesday, May 24, 2011 2:24 PM

O.I.E. Terrestrial Animal Health Standards Commission and prion (TSE) disease reporting 2011


http://transmissiblespongiformencephalopathy.blogspot.com/2011/05/oie-terrestrial-animal-health-standards.html





Monday, November 30, 2009

USDA AND OIE COLLABORATE TO EXCLUDE ATYPICAL SCRAPIE NOR-98 ANIMAL HEALTH CODE

http://nor-98.blogspot.com/2009/11/usda-and-oie-collaborate-to-exclude.html




IT is simply amazing to me how the OIE picks and chooses on what scrapie cases to report from what country, while never reporting cases the same way for the USA.


AGAIN, I ask, why is it that the USA, Canada, and Mexico, i.e. North America, why is it that all there animal TSEs (including Scrapie, and should be atypical scrapie, but the USDA and the OIE made atypical Nor-98 scrapie a legal commodity), but why is it that the USA, Canada, and Mexico, do not get there Scrapie cases reported to the public and posted on their site and or in there e-alerts ? it’s like the USA does not have Scrapie cases or any other TSE prion disease, if you go by what the OIE reports. SO again, why is it the OIE does not report animal TSE for North America, the same way it reports it for countries from the Middle East ?




Wednesday, February 08, 2012


Scrapie, Israel via OIE 02/02/2012



From: Terry S. Singeltary Sr.

Sent: Wednesday, February 08, 2012 10:28 AM

To: BSE-L BSE-L

Cc: hmb-central@icba.org.il ; delegation-israel@eeas.europa.eu ; Cvo_vsah@moag.gov.il ; galonn@moag.gov.il ; CJDVOICE CJDVOICE ; bloodcjd bloodcjd

Subject: Scrapie, Israel via OIE 02/02/2012



http://scrapie-usa.blogspot.com/2012/02/scrapie-israel-via-oie-02022012.html






Increased Atypical Scrapie Detections




Press reports indicate that increased surveillance is catching what otherwise would have been unreported findings of atypical scrapie in sheep. In 2009, five new cases have been reported in Quebec, Ontario, Alberta, and Saskatchewan. With the exception of Quebec, all cases have been diagnosed as being the atypical form found in older animals. Canada encourages producers to join its voluntary surveillance program in order to gain scrapie-free status. The World Animal Health will not classify Canada as scrapie-free until no new cases are reported for seven years. The Canadian Sheep Federation is calling on the government to fund a wider surveillance program in order to establish the level of prevalence prior to setting an eradication date. Besides long-term testing, industry is calling for a compensation program for farmers who report unusual deaths in their flocks.




http://gain.fas.usda.gov/Recent%20GAIN%20Publications/This%20Week%20in%20Canadian%20Agriculture%20%20%20%20%20Issue%2028_Ottawa_Canada_11-6-2009.pdf







J Vet Diagn Invest 21:454-463 (2009)




Nor98 scrapie identified in the United States



Christie M. Loiacono,' Bruce V. Thomsen, S. Mark Hall, Matti Kiupe!, Diane Sutton, Katherine O'Rourke, Bradd Barr, Lucy Anthenill, Deiwyn Keane



Abstract.



A distinct strain of scrapic identified in sheep of Norway in 1998 has since been identified in numerous countries throughout Europe. The disease is known as Nor98 or Not-98-like scrapic. among other names. Distinctions between classic scrapie and Nor98 scrapie are made based on histopathologv and immunodiagnostic results. There are also differences in the epidemiology, typical signalment, and likelihood of clinical signs being observed. In addition, sheep that have genotypes associated with resistance to classic scrapie are not spared from Nor98 disease. The various differences between classic and Nor98 scrapie have been consistently reported in the vast majority of cases described across Europe. The current study describes in detail the patholo gic changes and diagnostic results of the first 6 cases of' Nor98 scrapic disease diagnosed in sheep of the United States.

Key words: Hisiopathology: Nor98: PrP imniunolabeling; scrapie: sheep.




snip...



Results


Case I

The first case identified as consistent with Nor98 scrapie had nonclassic PrP distribution in brain tissue, no PrPSC in lymph tissue, and nonclassic migration of protein bands on a Western blot test. The animal was an aged, mottled-faced ewe that was traced back to a commercial flock in Wyoming. ...

Case 2

The second case was a clinically normal 8-year-old Suffolk ewe that had been in a quarantined flock for 5 years at a USDA facility in Iowa.

Case 3

A 16-year-old, white-faced, cross-bred wether was born to a black-faced ewe. He lived his entire life as a pet on a farm in California.

Case 4

The fourth case of Nor98 scrapie was identified in an approximately 8-year-old Dorset ewe that was born into a flock of approximately 20 ewes in Indiana.

Case 5

The fifth case was a clinically normal, approximately 3-year-old, white-faced, cross-bred ewe from an approximately 400 head commercial flock in Minnesota.

Case 6

The sixth case of Nor98 scrapie was identified in a 4-year-old, white-faced ewe that was purchased and added to a commercial flock in Pennsylvania


snip...


see full text ;



http://ddr.nal.usda.gov/bitstream/10113/33943/1/IND44241920.pdf








http://scrapie-usa.blogspot.com/





Sunday, April 18, 2010

SCRAPIE AND ATYPICAL SCRAPIE TRANSMISSION STUDIES A REVIEW 2010

http://scrapie-usa.blogspot.com/2010/04/scrapie-and-atypical-scrapie.html







Thursday, February 23, 2012


Atypical Scrapie NOR-98 confirmed Alberta Canada sheep January 2012 (USA UPDATE ALSO)


http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/atypical-scrapie-nor-98-confirmed.html





I see again that the OIE has done little to help eradicate all animal TSE from the globe, and in fact in my opinion, have help enhance the spread of BSE and other animal TSE globally by their industry friendly regulations. I tried to warn the OIE in 2002 about CWD and the potential, but very real threat of CWD to humans. I was told that they were seriously considering this. what happened ? NOW, the OIE and the USDA collaborate to make legal the trading of all strains of atypical BSE legal, and in fact have done so with the atypical scrapie, when science has made perfectly clear the risk factors to humans and other species. I have said it once (see below), and i will say again ;




"THE OIE has now shown they are nothing more than a National Trading Brokerage for all strains of animal TSE. AS i said before, OIE should hang up there jock strap now, since it appears they will buckle every time a country makes some political hay about trade protocol, commodities and futures. IF they are not going to be science based, they should do everyone a favor and dissolve there organization."




NOW, some history on the failed OIE BSE/TSE policy, and why the OIE allowed BSE and other TSE to spread around the globe $$$




snip...see full text ;



http://transmissiblespongiformencephalopathy.blogspot.com/2010/12/oie-global-conference-on-wildlife.html





Saturday, March 10, 2012


CWD, GAME FARMS, urine, feces, soil, lichens, and banned mad cow protein feed CUSTOM MADE for deer and elk


http://chronic-wasting-disease.blogspot.com/2012/03/cwd-game-farms-urine-feces-soil-lichens.html






Saturday, March 10, 2012


Enhanced Surveillance Strategies for Detecting and Monitoring Chronic Wasting Disease in Free-Ranging Cervids Open-File Report 2012–1036 National Wildlife Health Center


Open-File Report 2012–1036


http://chronic-wasting-disease.blogspot.com/2012/03/enhanced-surveillance-strategies-for.html





2012


PIG IN A POKE !!!





Sunday, January 29, 2012



Prion Disease Risks in the 21st Century 2011 PDA European Virus-TSE Safety Dr. Detwiler



Dr. Detwiler published Prion Disease Risks in the 21st Century 2011 PDA European Virus-TSE Safety Forum\Presentations TSE\ Page 33 and 34 of 44 ;



http://www.pda.org/




http://transmissiblespongiformencephalopathy.blogspot.com/2012/01/prion-disease-risks-in-21st-century.html





10,000,000+ LBS. of PROHIBITED BANNED MAD COW FEED I.E. BLOOD LACED MBM IN COMMERCE USA 2007


Date: March 21, 2007 at 2:27 pm PST

RECALLS AND FIELD CORRECTIONS: VETERINARY MEDICINES -- CLASS II

___________________________________

PRODUCT

Bulk cattle feed made with recalled Darling's 85% Blood Meal, Flash Dried, Recall # V-024-2007

CODE

Cattle feed delivered between 01/12/2007 and 01/26/2007

RECALLING FIRM/MANUFACTURER

Pfeiffer, Arno, Inc, Greenbush, WI. by conversation on February 5, 2007.

Firm initiated recall is ongoing.

REASON

Blood meal used to make cattle feed was recalled because it was cross- contaminated with prohibited bovine meat and bone meal that had been manufactured on common equipment and labeling did not bear cautionary BSE statement.

VOLUME OF PRODUCT IN COMMERCE

42,090 lbs.

DISTRIBUTION

WI

___________________________________

PRODUCT

Custom dairy premix products: MNM ALL PURPOSE Pellet, HILLSIDE/CDL Prot- Buffer Meal, LEE, M.-CLOSE UP PX Pellet, HIGH DESERT/ GHC LACT Meal, TATARKA, M CUST PROT Meal, SUNRIDGE/CDL PROTEIN Blend, LOURENZO, K PVM DAIRY Meal, DOUBLE B DAIRY/GHC LAC Mineral, WEST PIONT/GHC CLOSEUP Mineral, WEST POINT/GHC LACT Meal, JENKS, J/COMPASS PROTEIN Meal, COPPINI - 8# SPECIAL DAIRY Mix, GULICK, L-LACT Meal (Bulk), TRIPLE J - PROTEIN/LACTATION, ROCK CREEK/GHC MILK Mineral, BETTENCOURT/GHC S.SIDE MK-MN, BETTENCOURT #1/GHC MILK MINR, V&C DAIRY/GHC LACT Meal, VEENSTRA, F/GHC LACT Meal, SMUTNY, A- BYPASS ML W/SMARTA, Recall # V-025-2007

CODE

The firm does not utilize a code - only shipping documentation with commodity and weights identified.

RECALLING FIRM/MANUFACTURER

Rangen, Inc, Buhl, ID, by letters on February 13 and 14, 2007. Firm initiated recall is complete.

REASON

Products manufactured from bulk feed containing blood meal that was cross contaminated with prohibited meat and bone meal and the labeling did not bear cautionary BSE statement.

VOLUME OF PRODUCT IN COMMERCE

9,997,976 lbs.

DISTRIBUTION

ID and NV

END OF ENFORCEMENT REPORT FOR MARCH 21, 2007



http://www.fda.gov/bbs/topics/enforce/2007/ENF00996.html





NEW URL

http://www.fda.gov/Safety/Recalls/EnforcementReports/2007/ucm120446.htm





Thursday, March 19, 2009

MILLIONS AND MILLIONS OF POUNDS OF MAD COW FEED IN COMMERCE USA WITH ONGOING 12 YEARS OF DENIAL

http://madcowfeed.blogspot.com/2009/03/millions-and-millions-of-pounds-of-mad.html





Tuesday, March 2, 2010

Animal Proteins Prohibited in Ruminant Feed/Adulterated/Misbranded Rangen Inc 2/11/10 USA

http://madcowfeed.blogspot.com/2010/03/animal-proteins-prohibited-in-ruminant.html





Monday, March 1, 2010

ANIMAL PROTEIN I.E. MAD COW FEED IN COMMERCE A REVIEW 2010

http://madcowfeed.blogspot.com/2010/03/animal-protien-ie-mad-cow-feed-in.html





Saturday, November 6, 2010

TAFS1 Position Paper on Position Paper on Relaxation of the Feed Ban in the EU

Berne, 2010 TAFS INTERNATIONAL FORUM FOR TRANSMISSIBLE ANIMAL DISEASES AND FOOD SAFETY a non-profit Swiss Foundation


http://madcowfeed.blogspot.com/2010/11/tafs1-position-paper-on-position-paper.html






Archive Number 20101206.4364 Published Date 06-DEC-2010 Subject PRO/AH/EDR>


Prion disease update 2010 (11) PRION DISEASE UPDATE 2010 (11)


http://www.promedmail.org/direct.php?id=20101206.4364





Sunday, February 5, 2012 February 2012

Update on Feed Enforcement Activities to Limit the Spread of BSE

http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/february-2012-update-on-feed.html






Harvard Risk Assessment of Bovine Spongiform Encephalopathy Update, October 31, 2005 INTRODUCTION The United States Department of Agriculture’s Food Safety and Inspection Service (FSIS) held a public meeting on July 25, 2006 in Washington, D.C. to present findings from the Harvard Risk Assessment of Bovine Spongiform Encephalopathy Update, October 31, 2005 (report and model located on the FSIS website:

http://www.fsis.usda.gov/Science/Risk_Assessments/index.asp).






Comments on technical aspects of the risk assessment were then submitted to FSIS.

Comments were received from Food and Water Watch, Food Animal Concerns Trust (FACT), Farm Sanctuary, R-CALF USA, Linda A Detwiler, and Terry S. Singeltary.

This document provides itemized replies to the public comments received on the 2005 updated Harvard BSE risk assessment. Please bear the following points in mind:

http://www.fsis.usda.gov/PDF/BSE_Risk_Assess_Response_Public_Comments.pdf






Owens, Julie From: Terry S. Singeltary Sr. [flounder9@verizon.net]

Sent: Monday, July 24, 2006 1:09 PM

To: FSIS RegulationsComments

Subject: [Docket No. FSIS-2006-0011] FSIS Harvard Risk Assessment of Bovine Spongiform Encephalopathy (BSE) Page 1 of 98

http://www.fsis.usda.gov/OPPDE/Comments/2006-0011/2006-0011-1.pdf






FSIS, USDA, REPLY TO SINGELTARY

http://www.fsis.usda.gov/PDF/BSE_Risk_Assess_Response_Public_Comments.pdf






Monday, October 10, 2011

EFSA Journal 2011 The European Response to BSE: A Success Story

snip...

EFSA and the European Centre for Disease Prevention and Control (ECDC) recently delivered a scientific opinion on any possible epidemiological or molecular association between TSEs in animals and humans (EFSA Panel on Biological Hazards (BIOHAZ) and ECDC, 2011). This opinion confirmed Classical BSE prions as the only TSE agents demonstrated to be zoonotic so far but the possibility that a small proportion of human cases so far classified as "sporadic" CJD are of zoonotic origin could not be excluded. Moreover, transmission experiments to non-human primates suggest that some TSE agents in addition to Classical BSE prions in cattle (namely L-type Atypical BSE, Classical BSE in sheep, transmissible mink encephalopathy (TME) and chronic wasting disease (CWD) agents) might have zoonotic potential.

snip...


http://www.efsa.europa.eu/en/efsajournal/pub/e991.htm?emt=1




http://www.efsa.europa.eu/en/efsajournal/doc/e991.pdf






see follow-up here about North America BSE Mad Cow TSE prion risk factors, and the ever emerging strains of Transmissible Spongiform Encephalopathy in many species here in the USA, including humans ;


http://transmissiblespongiformencephalopathy.blogspot.com/2011/10/efsa-journal-2011-european-response-to.html







Thursday, August 12, 2010

Seven main threats for the future linked to prions

First threat

The TSE road map defining the evolution of European policy for protection against prion diseases is based on a certain numbers of hypotheses some of which may turn out to be erroneous. In particular, a form of BSE (called atypical Bovine Spongiform Encephalopathy), recently identified by systematic testing in aged cattle without clinical signs, may be the origin of classical BSE and thus potentially constitute a reservoir, which may be impossible to eradicate if a sporadic origin is confirmed.

***Also, a link is suspected between atypical BSE and some apparently sporadic cases of Creutzfeldt-Jakob disease in humans. These atypical BSE cases constitute an unforeseen first threat that could sharply modify the European approach to prion diseases.

Second threat

snip...


http://www.neuroprion.org/en/np-neuroprion.html








Saturday, March 5, 2011


MAD COW ATYPICAL CJD PRION TSE CASES WITH CLASSIFICATIONS PENDING ON THE RISE IN NORTH AMERICA


http://transmissiblespongiformencephalopathy.blogspot.com/2011/03/mad-cow-atypical-cjd-prion-tse-cases.html








Sunday, February 12, 2012


National Prion Disease Pathology Surveillance Center Cases Examined1 (August 19, 2011) including Texas



http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/national-prion-disease-pathology.html








Friday, March 09, 2012

Experimental H-type and L-type bovine spongiform encephalopathy in cattle: observation of two clinical syndromes and diagnostic challenges

Research article

http://bse-atypical.blogspot.com/2012/03/experimental-h-type-and-l-type-bovine.html






Thursday, February 16, 2012

Bovine Spongiform Encephalopathy BSE

31 USA SENATORS ASK PRESIDENT OBAMA TO HELP SPREAD MAD COW DISEASE 2012

http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/bovine-spongiform-encephalopathy-bse-31.html





Thursday, February 23, 2012

EIGHT FORMER SECRETARIES OF AGRICULTURE SPEAKING AT USDA'S 2012 AGRICULTURE OUTLOOK FORUM INDUCTED INTO USA MAD COW HALL OF SHAME

http://madcowusda.blogspot.com/2012/02/eight-former-secretaries-of-agriculture.html





Wednesday, July 23, 2008


Audit says USDA lost track of imported cattle Report No. 50601-0012-Ch March 2008


http://usdameatexport.blogspot.com/2008/07/audit-says-usda-lost-track-of-imported.html




http://usdameatexport.blogspot.com/2007/11/transcript-of-questions-and-answers.html





Tuesday, December 1, 2009


IMPORTATION OF CANADIAN CATTLE, BISON, SHEEP, AND GOATS INTO THE UNITED STATES 12/1/09


http://usdameatexport.blogspot.com/2009/12/importation-of-canadian-cattle-bison.html




http://usdameatexport.blogspot.com/






Friday, January 20, 2012

South Korea Lifts Canadian Beef Ban

http://usdavskorea.blogspot.com/2012/01/south-korea-lifts-canadian-beef-ban.html





Saturday, January 21, 2012

Quick facts about mad cow disease

http://transmissiblespongiformencephalopathy.blogspot.com/2012/01/quick-facts-about-mad-cow-disease.html





Terry S. Singeltary Sr. on the Creutzfeldt-Jakob Disease Public Health Crisis


http://www.youtube.com/watch?v=zf3lfz9NrT4




http://www.youtube.com/watch?v=c0tWkNvhO4g




http://www.youtube.com/watch?v=zf3lfz9NrT4&feature=results_main&playnext=1&list=PL780BE2AF0B62A944






full text with source references ;



http://transmissiblespongiformencephalopathy.blogspot.com/2011/08/terry-singeltary-sr-on-creutzfeldt.html






Geographical BSE risk assessment and its impact on disease detection and dissemination


Original Research Article


Preventive Veterinary Medicine, Available online 1 February 2012,


Mo Salman, Vittorio Silano, Dagmar Heim, Joachim Kreysa


Preventive Veterinary Medicine


1 February 2012


Geographical BSE risk assessment and its impact on disease detection and dissemination


Salman M, Silano V, Heim D, Kreysa J.


Source


Campus Stop 1644, Animal Population Health Institute, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523-1644, USA.


Abstract


Bovine Spongiform Encephalopathy (BSE) rapidly evolved into an issue of major public concern particularly when, in 1996, evidence was provided that this disease had crossed the species barrier and infected humans in the UK with what has become known as "variant Creutzfeldt Jakob Disease" (vCJD). The aim of this paper is to describe the European Geographical BSE risk assessment (GBR) that was successfully used for assessing the qualitative likelihood that BSE could be present in a country where it was not yet officially recognized. It also discusses how this can lead to risk-based and therefore preventive management of BSE at national and international levels. The basic assumption of the GBR method is that the BSE agent is initially introduced into a country's domestic cattle production system through the importation of contaminated feedstuffs or live cattle. This is referred to as an "external challenge". The ability of the system to cope with such a challenge is, in turn, referred to as its "stability": a stable system will not allow the BSE agent to propagate and amplify following its introduction, while an unstable system will. The BSE-status of a country assessed by this system was used by the European Commission as the basis for trade legislation rules for cattle and their products. The GBR was an invaluable tool in evaluating the potential global spread of BSE as it demonstrated how a disease could be transferred through international trade. This was shown to be a critical factor to address in reducing the spread and amplification of BSE throughout the world. Furthermore, GBR resulted in the implementation of additional measures and management activities both to improve surveillance and to prevent transmission within the cattle population.



Copyright © 2012 Elsevier B.V. All rights reserved.


http://www.sciencedirect.com/science/article/pii/S0167587712000244






see more here ;



http://transmissiblespongiformencephalopathy.blogspot.com/2012/02/bovine-spongiform-encephalopathy-bse-31.html







IN SHORT, AND IN A NUT SHELL ;



(Adopted by the International Committee of the OIE on 23 May 2006)



11. Information published by the OIE is derived from appropriate declarations made by the official Veterinary Services of Member Countries. The OIE is not responsible for inaccurate publication of country disease status based on inaccurate information or changes in epidemiological status or other significant events that were not promptly reported to the Central Bureau,



http://www.oie.int/eng/Session2007/RF2006.pdf








layperson



Terry S. Singeltary Sr.
P.O. Box 42
Bacliff, Texas USA 77518
flounder9@verizon.net

Iowa Legislature gives go ahead for more Mad Cow Dead Stock Downer Cows to your children via USDA NSLP

Saturday, March 3, 2012

Iowa Legislature gives the green light for more dead stock downer cows to be fed to your children i.e. mad cow CJD

 

http://downercattle.blogspot.com/2012/03/iowa-legislature-gives-green-light-for.html

 

 

 

 

TSS