Contact: Lyndsay Cole (970) 494-7410 
Update from APHIS Regarding Release of the Final Report on the BSE 
Epidemiological Investigation 
Today, USDA is releasing its final report on the epidemiological 
investigation of a dairy cow from California that tested positive for bovine 
spongiform encephalopathy (BSE) in April 2012. This epidemiological report is 
the result of months of close coordination with the U.S. Food and Drug 
Administration (FDA), the California Department of Food and Agriculture (CDFA), 
local officials, and the associated dairy and rendering facility.
In accordance with World Organization for Animal Health guidance, USDA 
conducted a thorough epidemiological investigation following the BSE detection. 
This included on-the-ground investigations and records review from the rendering 
facility, the index farm, and associated premises, as well as traceback for 
progeny and birth cohorts of the index cow. The results of this thorough 
investigation confirmed that at no time was the U.S. food supply or human health 
at risk, and that the United States’ longstanding system of interlocking 
safeguards against BSE continues to be effective.
This case was found in an animal that was sampled for the disease at a 
rendering facility in central California. This animal was never presented for 
slaughter for human consumption, so at no time presented a risk to the food 
supply, or to human health in the United States.
The index animal was a 10 year 7 month-old Holstein cow from a central 
California dairy. The animal was humanely euthanized after it developed lameness 
and became recumbent, and was sampled by a renderer contracted to collect 
samples as part of USDA’s ongoing BSE surveillance. Results from 
immunohistochemistry and Western blot tests at USDA’s National Veterinary 
Services Laboratories (NVSL) confirmed the animal positive for atypical BSE. 
Samples were also sent to the World Organization for Animal Health (OIE) 
reference laboratories in Canada and England. The laboratories confirmed that 
the index cow was positive for atypical (L-type) BSE.
As a result of on-the-ground investigation and records review, USDA and 
CDFA identified only one live offspring of the cow, which was humanely 
euthanized and found to be negative for BSE. No birth cohorts of the index 
animal were found alive. 
The carcass of the index animal (along with approximately 90 other 
carcasses being held at the renderer’s transfer station), were disposed of in a 
landfill in accordance with all Federal, State and local regulations. The 
carcass of the index animal did not enter the human or animal food chain.
In conjunction with USDA’s investigation, FDA and CDFA conducted an 
extensive feed investigation. Twelve feed suppliers were identified to the index 
premises; one of which was no longer in business. The remaining 11 were found to 
be in compliance with FDA and CDFA regulations and requirements. FDA has 
released a full report on the feed investigation. It is available at 
www.fda.gov. 
The United States has a longstanding system of three interlocking 
safeguards against BSE that protects human and animal health, the most important 
of which is the removal of specified risk materials – or the parts of an animal 
that would contain the BSE agent should an animal have the disease – from all 
animals presented for slaughter in the United States. The second safeguard is a 
strong feed ban that protects cattle from the disease. The third safeguard—which 
led to this detection— is our ongoing BSE surveillance program that allows USDA 
to detect the disease if it exists at very low levels in the U.S. cattle 
population and provides assurances to consumers and our international trading 
partners that the interlocking system of safeguards in place to prevent BSE are 
working.
View Final Report
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advisories are available on the Internet and through Really Simple Syndication 
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USDA is an equal opportunity provider and employer. To file a complaint of 
discrimination, write: USDA, Office of the Assistant Secretary for Civil Rights, 
Office of Adjudication, 1400 Independence Ave., SW, Washington, DC 20250-9410 or 
call (866) 632-9992 (Toll-free Customer Service), (800) 877-8339 (Local or 
Federal relay), (866) 377-8642 (Relay voice users).
SUMMARY REPORT CALIFORNIA BOVINE SPONGIFORM ENCEPHALOPATHY CASE 
INVESTIGATION JULY 2012
Summary Report BSE 2012
Executive Summary 
Saturday, August 4, 2012 
Final Feed Investigation Summary - California BSE Case - July 2012 
TSS

 
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